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A population-based study of patterns of care for muscle-invasive bladder cancer in Sweden

Jahnson, Staffan ; Damm, Ole ; Hellsten, Sverker LU ; Holmang, Sten ; Liedberg, Fredrik ; Ljungberg, Borje ; Malmstrom, Per-Uno ; Månsson, Wiking LU ; Stromberg, Fredrik and Wijkstom, Hans (2009) In Scandinavian Journal of Urology and Nephrology 43(4). p.271-276
Abstract
Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnosed with such disease since 1997. Results from 1997-2003 were analysed regarding curative-intent treatment given within 3-6 months of diagnosis of muscle-invasive bladder cancer. Results. In total, 3463 patients with clinical T2-T4 bladder cancer were included in the analysis. Of those patients, 1426 (41%) received curative-intent treatment in the... (More)
Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnosed with such disease since 1997. Results from 1997-2003 were analysed regarding curative-intent treatment given within 3-6 months of diagnosis of muscle-invasive bladder cancer. Results. In total, 3463 patients with clinical T2-T4 bladder cancer were included in the analysis. Of those patients, 1426 (41%) received curative-intent treatment in the form of radiotherapy (285, 20%) or cystectomy (1141, 80%). Male gender, age 76 years, favourable TNM category and registration at a high-volume hospital were associated with such treatment. Curative-intent treatment was given to significantly more patients registered at high-volume hospitals (1003/2227, 45%) than at low-volume hospitals (423/1235, 34%) (2=37.7, p0.00001). Cystectomy was performed more often in those registered at high-volume than at low-volume hospitals (826/2227, 37%, and 316/1235, 26%, respectively, 2=47.3, p0.00001). Conclusions. Lower rates of curative-intent treatment were found in patients registered at low-volume than at high-volume facilities, and the same was seen when comparing females with males, and patients aged 76-80 years with younger patients. Since many of these bladder cancer patients were registered at and eventually treated at hospitals handling fewer than 10 such cases annually, it seems desirable to concentrate treatment of this disease at more specialized centres. (Less)
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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
national, Bladder cancer, curative treatment, patterns of care, register
in
Scandinavian Journal of Urology and Nephrology
volume
43
issue
4
pages
271 - 276
publisher
Taylor & Francis
external identifiers
  • wos:000269602800003
  • scopus:70249088409
  • pmid:19424934
ISSN
0036-5599
DOI
10.1080/00365590902909778
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Urology, Lund (013077000), Urology (013243400)
id
35281274-a500-4237-bf49-530ae50fab18 (old id 1474926)
date added to LUP
2016-04-01 14:52:52
date last changed
2021-09-15 05:14:37
@article{35281274-a500-4237-bf49-530ae50fab18,
  abstract     = {Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnosed with such disease since 1997. Results from 1997-2003 were analysed regarding curative-intent treatment given within 3-6 months of diagnosis of muscle-invasive bladder cancer. Results. In total, 3463 patients with clinical T2-T4 bladder cancer were included in the analysis. Of those patients, 1426 (41%) received curative-intent treatment in the form of radiotherapy (285, 20%) or cystectomy (1141, 80%). Male gender, age 76 years, favourable TNM category and registration at a high-volume hospital were associated with such treatment. Curative-intent treatment was given to significantly more patients registered at high-volume hospitals (1003/2227, 45%) than at low-volume hospitals (423/1235, 34%) (2=37.7, p0.00001). Cystectomy was performed more often in those registered at high-volume than at low-volume hospitals (826/2227, 37%, and 316/1235, 26%, respectively, 2=47.3, p0.00001). Conclusions. Lower rates of curative-intent treatment were found in patients registered at low-volume than at high-volume facilities, and the same was seen when comparing females with males, and patients aged 76-80 years with younger patients. Since many of these bladder cancer patients were registered at and eventually treated at hospitals handling fewer than 10 such cases annually, it seems desirable to concentrate treatment of this disease at more specialized centres.},
  author       = {Jahnson, Staffan and Damm, Ole and Hellsten, Sverker and Holmang, Sten and Liedberg, Fredrik and Ljungberg, Borje and Malmstrom, Per-Uno and Månsson, Wiking and Stromberg, Fredrik and Wijkstom, Hans},
  issn         = {0036-5599},
  language     = {eng},
  number       = {4},
  pages        = {271--276},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Urology and Nephrology},
  title        = {A population-based study of patterns of care for muscle-invasive bladder cancer in Sweden},
  url          = {http://dx.doi.org/10.1080/00365590902909778},
  doi          = {10.1080/00365590902909778},
  volume       = {43},
  year         = {2009},
}