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Life-time adversities, reported thirteen years after a suicide attempt: relationship to recovery, 5HTTLPR genotype, and past and present morbidity.

Vang, Fredrik LU ; Lindström, Mats LU ; Sunnqvist, Charlotta LU ; Bah-Rösman, Jessica; Johanson, Aki LU and Träskman Bendz, Lil LU (2009) In Archives of Suicide Research 13(3). p.214-229
Abstract
In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic... (More)
In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic morbidity. 5-HTTLPR genotype did not affect long-term recovery. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
outcome, life-events, follow-up, gene, self-harm, suicide
in
Archives of Suicide Research
volume
13
issue
3
pages
214 - 229
publisher
Routledge
external identifiers
  • wos:000276408000002
  • scopus:69849094292
ISSN
1543-6136
DOI
10.1080/13811110903044328
language
English
LU publication?
yes
id
efb8bef4-4eba-4195-ab78-99b333b2c799 (old id 1480548)
date added to LUP
2009-09-30 09:38:54
date last changed
2017-01-01 05:19:52
@article{efb8bef4-4eba-4195-ab78-99b333b2c799,
  abstract     = {In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic morbidity. 5-HTTLPR genotype did not affect long-term recovery.},
  author       = {Vang, Fredrik and Lindström, Mats and Sunnqvist, Charlotta and Bah-Rösman, Jessica and Johanson, Aki and Träskman Bendz, Lil},
  issn         = {1543-6136},
  keyword      = {outcome,life-events,follow-up,gene,self-harm,suicide},
  language     = {eng},
  number       = {3},
  pages        = {214--229},
  publisher    = {Routledge},
  series       = {Archives of Suicide Research},
  title        = {Life-time adversities, reported thirteen years after a suicide attempt: relationship to recovery, 5HTTLPR genotype, and past and present morbidity.},
  url          = {http://dx.doi.org/10.1080/13811110903044328},
  volume       = {13},
  year         = {2009},
}