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Clinical value of fibrillatory wave amplitude on surface ECG in patients with persistent atrial fibrillation

Nault, Isabelle; Lellouche, Nicolas; Matsuo, Seiichiro; Knecht, Sebastien; Wright, Matthew; Lim, Kang-Teng; Sacher, Frederic; Platonov, Pyotr LU ; Deplagne, Antoine and Bordachar, Pierre, et al. (2009) In Journal of Interventional Cardiac Electrophysiology 26(1). p.11-19
Abstract
We postulated that amplitude of fibrillatory (F)-wave in patients with persistent AF would correlate with clinical characteristics and outcome in patients undergoing catheter ablation for AF. Maximal and mean amplitude of F-waves were measured in V1 and lead II in 90 patients prior to ablation for persistent AF. F-wave amplitudes were correlated to clinical, echocardiographic variables, and outcome. F-wave a parts per thousand yenaEuro parts per thousand 0.1 mV in lead II and V1was correlated with younger age and shorter AF history, and in lead II only was correlated with a smaller left atrium. Higher F-wave amplitude at baseline predicted AF termination during ablation. Maximal amplitude of a parts per thousand yenaEuro parts per thousand... (More)
We postulated that amplitude of fibrillatory (F)-wave in patients with persistent AF would correlate with clinical characteristics and outcome in patients undergoing catheter ablation for AF. Maximal and mean amplitude of F-waves were measured in V1 and lead II in 90 patients prior to ablation for persistent AF. F-wave amplitudes were correlated to clinical, echocardiographic variables, and outcome. F-wave a parts per thousand yenaEuro parts per thousand 0.1 mV in lead II and V1was correlated with younger age and shorter AF history, and in lead II only was correlated with a smaller left atrium. Higher F-wave amplitude at baseline predicted AF termination during ablation. Maximal amplitude of a parts per thousand yenaEuro parts per thousand 0.07 mV predicted AF termination by ablation with 82%/79% sensitivity and 68%/73% specificity in V1/lead II respectively. An association between F-wave amplitude and AF recurrence was observed. Forty-three percent of patients with mean f wave amplitude < 0.05 in lead V1 had AF recurrence compared to 12% of those with F-wave a parts per thousand yenaEuro parts per thousand 0.05 (p = 0.004). Longer AF duration, older age and larger LA size are associated with fine AF amplitude. High F-wave amplitude predicts procedural termination of arrhyhmia in patients with persistent AF and freedom from AF upon follow-up. (Less)
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Contribution to journal
publication status
published
subject
keywords
Coarse atrial fibrillation, Catheter ablation, amplitude, Fibrillatory wave, Electrocardiogram, Arrhythmia, Atrial fibrillation
in
Journal of Interventional Cardiac Electrophysiology
volume
26
issue
1
pages
11 - 19
publisher
Springer
external identifiers
  • wos:000269956300003
  • scopus:70349316689
ISSN
1572-8595
DOI
10.1007/s10840-009-9398-3
language
English
LU publication?
yes
id
edcc2dd7-6686-475e-98b6-00002c0d00c3 (old id 1489993)
date added to LUP
2009-10-21 10:28:10
date last changed
2017-08-13 03:45:57
@article{edcc2dd7-6686-475e-98b6-00002c0d00c3,
  abstract     = {We postulated that amplitude of fibrillatory (F)-wave in patients with persistent AF would correlate with clinical characteristics and outcome in patients undergoing catheter ablation for AF. Maximal and mean amplitude of F-waves were measured in V1 and lead II in 90 patients prior to ablation for persistent AF. F-wave amplitudes were correlated to clinical, echocardiographic variables, and outcome. F-wave a parts per thousand yenaEuro parts per thousand 0.1 mV in lead II and V1was correlated with younger age and shorter AF history, and in lead II only was correlated with a smaller left atrium. Higher F-wave amplitude at baseline predicted AF termination during ablation. Maximal amplitude of a parts per thousand yenaEuro parts per thousand 0.07 mV predicted AF termination by ablation with 82%/79% sensitivity and 68%/73% specificity in V1/lead II respectively. An association between F-wave amplitude and AF recurrence was observed. Forty-three percent of patients with mean f wave amplitude &lt; 0.05 in lead V1 had AF recurrence compared to 12% of those with F-wave a parts per thousand yenaEuro parts per thousand 0.05 (p = 0.004). Longer AF duration, older age and larger LA size are associated with fine AF amplitude. High F-wave amplitude predicts procedural termination of arrhyhmia in patients with persistent AF and freedom from AF upon follow-up.},
  author       = {Nault, Isabelle and Lellouche, Nicolas and Matsuo, Seiichiro and Knecht, Sebastien and Wright, Matthew and Lim, Kang-Teng and Sacher, Frederic and Platonov, Pyotr and Deplagne, Antoine and Bordachar, Pierre and Derval, Nicolas and O'Neill, Mark D. and Klein, George J. and Hocini, Meleze and Jais, Pierre and Clementy, Jacques and Haissaguerre, Michel},
  issn         = {1572-8595},
  keyword      = {Coarse atrial fibrillation,Catheter ablation,amplitude,Fibrillatory wave,Electrocardiogram,Arrhythmia,Atrial fibrillation},
  language     = {eng},
  number       = {1},
  pages        = {11--19},
  publisher    = {Springer},
  series       = {Journal of Interventional Cardiac Electrophysiology},
  title        = {Clinical value of fibrillatory wave amplitude on surface ECG in patients with persistent atrial fibrillation},
  url          = {http://dx.doi.org/10.1007/s10840-009-9398-3},
  volume       = {26},
  year         = {2009},
}