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Smoking impacts endogenous estradiol and testosterone levels in young healthy women

C., Ellberg LU ; H., Olsson LU and H., Jernstrom LU (2017) American Association for Cancer Research (AACR) 108th Annual Meeting 2017 In Cancer Research 77(13 Suppl).
Abstract
Introduction: The purpose of the study was to elucidate the association between smoking and estradiol (E2) and testosterone (T) levels in young healthy women from highrisk families. Cigarette smoke contains multiple carcinogens and is considered a risk factor for breast cancer. However, tobacco also contains aromatase inhibiting substances, but the impact on hormonal levels in young women at the age when breast cancer is initiated is unclear and needs further elucidation. Material and methods Between 1996 and 2002, 258 healthy women from high-risk breast cancer families in Sweden were enrolled in a study on the impact of lifestyle factors in women
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organization
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type
Contribution to journal
publication status
published
subject
keywords
aromatase, BRCA1 protein, carcinogen, cigarette smoke, endogenous compound, estradiol, hormone, oral contraceptive agent, testosterone, adult, anthropometry, blood, breast cancer, breast feeding, cancer family, cancer risk, drug combination, female, gene mutation, human, lifestyle, linear regression analysis, luteal phase, major clinical study, nullipara, nurse, oral contraceptive use, pill, questionnaire, risk factor, smoking, statistical significance, Sweden, waist hip ratio
in
Cancer Research
volume
77
issue
13 Suppl
article number
Abstract 4263
publisher
American Association for Cancer Research Inc.
conference name
American Association for Cancer Research (AACR) 108th Annual Meeting 2017
conference location
Washington, DC, United States
conference dates
2017-04-01 - 2017-04-05
ISSN
1538-7445
DOI
10.1158/1538-7445.AM2017-4263
language
English
LU publication?
yes
id
149621a5-1c40-4dcd-af77-8fe0c2845f58
date added to LUP
2019-07-01 10:24:07
date last changed
2019-07-01 10:24:07
@misc{149621a5-1c40-4dcd-af77-8fe0c2845f58,
  abstract     = {Introduction: The purpose of the study was to elucidate the association between smoking and estradiol (E2) and testosterone (T) levels in young healthy women from highrisk families. Cigarette smoke contains multiple carcinogens and is considered a risk factor for breast cancer. However, tobacco also contains aromatase inhibiting substances, but the impact on hormonal levels in young women at the age when breast cancer is initiated is unclear and needs further elucidation. Material and methods Between 1996 and 2002, 258 healthy women from high-risk breast cancer families in Sweden were enrolled in a study on the impact of lifestyle factors in women },
  author       = {C., Ellberg and H., Olsson and H., Jernstrom},
  issn         = {1538-7445},
  language     = {eng},
  note         = {Conference Abstract},
  number       = {13 Suppl},
  publisher    = {American Association for Cancer Research Inc.},
  series       = {Cancer Research},
  title        = {Smoking impacts endogenous estradiol and testosterone levels in young healthy women},
  url          = {http://dx.doi.org/10.1158/1538-7445.AM2017-4263},
  doi          = {10.1158/1538-7445.AM2017-4263},
  volume       = {77},
  year         = {2017},
}