Advanced

Maternal use of oral decongestants and delivery outcome

Källén, Bengt LU (2009) In Salud i Ciencia 17(1). p.41-45
Abstract
The study extends a previous investigation on the use of oral decongestants during pregnancy with another 1 000 women (1 017 infants) who reported the use of such drugs in early pregnancy and 1 125 women (1 145 infants) who had such drugs prescribed later in pregnancy. The results on the beneficial delivery outcome after late use of the drugs with a reduced rate of preterm birth and low birth weight were verified and it was also shown that the rates of large-for-gestational age and heavy infants were increased. After early use of such drugs, no increased risk of congenital malformation was seen and previously published data on an association with certain malformations, thought to be due to vascular disruption, could not be supported. It is... (More)
The study extends a previous investigation on the use of oral decongestants during pregnancy with another 1 000 women (1 017 infants) who reported the use of such drugs in early pregnancy and 1 125 women (1 145 infants) who had such drugs prescribed later in pregnancy. The results on the beneficial delivery outcome after late use of the drugs with a reduced rate of preterm birth and low birth weight were verified and it was also shown that the rates of large-for-gestational age and heavy infants were increased. After early use of such drugs, no increased risk of congenital malformation was seen and previously published data on an association with certain malformations, thought to be due to vascular disruption, could not be supported. It is suggested that pregnancy rhinitis as an indication for the use of oral decongestants could be associated with a well functioning placenta and a good delivery outcome. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
malformations, congenital, low birth weight, oral decongestants, preterm birth
in
Salud i Ciencia
volume
17
issue
1
pages
41 - 45
publisher
Sociedad Iberoamericana de Información Científica (SIIC)
external identifiers
  • wos:000271275300007
  • scopus:70449393087
ISSN
1667-8990
language
Spanish
LU publication?
yes
id
10e12c03-adc8-4762-9501-541c3d3050cf (old id 1504718)
date added to LUP
2009-11-25 10:09:30
date last changed
2017-02-22 10:46:33
@article{10e12c03-adc8-4762-9501-541c3d3050cf,
  abstract     = {The study extends a previous investigation on the use of oral decongestants during pregnancy with another 1 000 women (1 017 infants) who reported the use of such drugs in early pregnancy and 1 125 women (1 145 infants) who had such drugs prescribed later in pregnancy. The results on the beneficial delivery outcome after late use of the drugs with a reduced rate of preterm birth and low birth weight were verified and it was also shown that the rates of large-for-gestational age and heavy infants were increased. After early use of such drugs, no increased risk of congenital malformation was seen and previously published data on an association with certain malformations, thought to be due to vascular disruption, could not be supported. It is suggested that pregnancy rhinitis as an indication for the use of oral decongestants could be associated with a well functioning placenta and a good delivery outcome.},
  author       = {Källén, Bengt},
  issn         = {1667-8990},
  keyword      = {malformations,congenital,low birth weight,oral decongestants,preterm birth},
  language     = {spa},
  number       = {1},
  pages        = {41--45},
  publisher    = {Sociedad Iberoamericana de Información Científica (SIIC)},
  series       = {Salud i Ciencia},
  title        = {Maternal use of oral decongestants and delivery outcome},
  volume       = {17},
  year         = {2009},
}