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Comparison Between Two Models for Interactions Between Electric and Magnetic Fields and Proteins in Cell Membranes

Halgamuge, Malka N.; Persson, Bertil R LU ; Salford, Leif LU ; Mendis, Priyan and Eberhardt, Jacob LU (2009) In Environmental Engineering Science 26(10). p.1473-1480
Abstract
Investigations on exposure to electromagnetic have generated conflicting results both in epidemiological and laboratory studies, leaving their possible health consequences largely inconclusive. One of the well-reported reasons for the discrepancies is that there is no generally accepted theory to describe the interactions between the very weak electromagnetic fields and the living cells. This work presents a critical evaluation of three theories that describes the effects of weak electromagnetic fields on channel proteins in the cell membrane. The forced ion vibration model appears to explain the opening of ion channel proteins for exposures to low-frequency magnetic fields in the mili-Tesla range. No resonance frequencies or amplitude... (More)
Investigations on exposure to electromagnetic have generated conflicting results both in epidemiological and laboratory studies, leaving their possible health consequences largely inconclusive. One of the well-reported reasons for the discrepancies is that there is no generally accepted theory to describe the interactions between the very weak electromagnetic fields and the living cells. This work presents a critical evaluation of three theories that describes the effects of weak electromagnetic fields on channel proteins in the cell membrane. The forced ion vibration model appears to explain the opening of ion channel proteins for exposures to low-frequency magnetic fields in the mili-Tesla range. No resonance frequencies or amplitude window effects are predicted in this method. We identify inconsistencies in the forced vibration model and show that the environmental magnetic fields that would be required to elicit opening of channel proteins are much stronger than predicted by the proposers of this model. The Ion Parametric Resonance model predicts a biological response at well-defined resonance frequencies for magnetic fields exceeding about 10 micro-Tesla. The oscillating magnetic field is assumed to act on proteins together with the earth's static magnetic field. This model predicts amplitude windows. We explain how a purely magnetic interaction, where in a two-stage ion magnetic resonance model, the conformation of a protein is changed under the influence of ions attached to its surface, which in turn, changes the function of the protein, can overcome the inherent signal-to-noise problem caused by electric thermal noise. The hydrogen nuclear polarization model predicts a biological response for oscillating magnetic field strengths above 0.1 micro-Tesla. The presence of a static magnetic field is required, and biological effects can be expected for frequencies below a few hundred hertz. All models except the forced vibration model can be applied for amplitude modulated microwaves. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
High Voltage Power Lines, Base Stations, electromagnetic field (EMF) exposure, Mobile Phones, Interaction Models, Biological Effects
in
Environmental Engineering Science
volume
26
issue
10
pages
1473 - 1480
publisher
Mary Ann Liebert, Inc.
external identifiers
  • wos:000270822200002
  • scopus:70449487638
ISSN
1092-8758
DOI
10.1089/ees.2009.0014
language
English
LU publication?
yes
id
37b14528-648e-498d-a417-481dd2681282 (old id 1506964)
date added to LUP
2009-11-23 13:05:44
date last changed
2017-12-10 04:15:34
@article{37b14528-648e-498d-a417-481dd2681282,
  abstract     = {Investigations on exposure to electromagnetic have generated conflicting results both in epidemiological and laboratory studies, leaving their possible health consequences largely inconclusive. One of the well-reported reasons for the discrepancies is that there is no generally accepted theory to describe the interactions between the very weak electromagnetic fields and the living cells. This work presents a critical evaluation of three theories that describes the effects of weak electromagnetic fields on channel proteins in the cell membrane. The forced ion vibration model appears to explain the opening of ion channel proteins for exposures to low-frequency magnetic fields in the mili-Tesla range. No resonance frequencies or amplitude window effects are predicted in this method. We identify inconsistencies in the forced vibration model and show that the environmental magnetic fields that would be required to elicit opening of channel proteins are much stronger than predicted by the proposers of this model. The Ion Parametric Resonance model predicts a biological response at well-defined resonance frequencies for magnetic fields exceeding about 10 micro-Tesla. The oscillating magnetic field is assumed to act on proteins together with the earth's static magnetic field. This model predicts amplitude windows. We explain how a purely magnetic interaction, where in a two-stage ion magnetic resonance model, the conformation of a protein is changed under the influence of ions attached to its surface, which in turn, changes the function of the protein, can overcome the inherent signal-to-noise problem caused by electric thermal noise. The hydrogen nuclear polarization model predicts a biological response for oscillating magnetic field strengths above 0.1 micro-Tesla. The presence of a static magnetic field is required, and biological effects can be expected for frequencies below a few hundred hertz. All models except the forced vibration model can be applied for amplitude modulated microwaves.},
  author       = {Halgamuge, Malka N. and Persson, Bertil R and Salford, Leif and Mendis, Priyan and Eberhardt, Jacob},
  issn         = {1092-8758},
  keyword      = {High Voltage Power Lines,Base Stations,electromagnetic field (EMF) exposure,Mobile Phones,Interaction Models,Biological Effects},
  language     = {eng},
  number       = {10},
  pages        = {1473--1480},
  publisher    = {Mary Ann Liebert, Inc.},
  series       = {Environmental Engineering Science},
  title        = {Comparison Between Two Models for Interactions Between Electric and Magnetic Fields and Proteins in Cell Membranes},
  url          = {http://dx.doi.org/10.1089/ees.2009.0014},
  volume       = {26},
  year         = {2009},
}