New directions of miniaturization within the biomarker research area
(2004) In Electrophoresis 25(21-22). p.3479-3491- Abstract
- An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel and liquid phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing play a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/151171
- author
- Marko-Varga, György LU ; Nilsson, Johan LU and Laurell, Thomas LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Review, Biomarker, Miniaturization
- in
- Electrophoresis
- volume
- 25
- issue
- 21-22
- pages
- 3479 - 3491
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000225679000002
- pmid:15565715
- scopus:10944250915
- ISSN
- 0173-0835
- DOI
- 10.1002/elps.200406109
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biomedical Engineering (011200011), Analytical Chemistry (S/LTH) (011001004)
- id
- 81a59a0d-2d2c-41b8-acd2-af7cd7caeb3c (old id 151171)
- date added to LUP
- 2016-04-01 12:09:36
- date last changed
- 2022-04-13 06:54:38
@article{81a59a0d-2d2c-41b8-acd2-af7cd7caeb3c, abstract = {{An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel and liquid phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing play a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.}}, author = {{Marko-Varga, György and Nilsson, Johan and Laurell, Thomas}}, issn = {{0173-0835}}, keywords = {{Review; Biomarker; Miniaturization}}, language = {{eng}}, number = {{21-22}}, pages = {{3479--3491}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Electrophoresis}}, title = {{New directions of miniaturization within the biomarker research area}}, url = {{http://dx.doi.org/10.1002/elps.200406109}}, doi = {{10.1002/elps.200406109}}, volume = {{25}}, year = {{2004}}, }