Advanced

New directions of miniaturization within the biomarker research area

Marko-Varga, György LU ; Nilsson, Johan LU and Laurell, Thomas LU (2004) In Electrophoresis 25(21-22). p.3479-3491
Abstract
An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel and liquid phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing play a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Review, Biomarker, Miniaturization
in
Electrophoresis
volume
25
issue
21-22
pages
3479 - 3491
publisher
John Wiley & Sons
external identifiers
  • wos:000225679000002
  • pmid:15565715
  • scopus:10944250915
ISSN
0173-0835
DOI
10.1002/elps.200406109
language
English
LU publication?
yes
id
81a59a0d-2d2c-41b8-acd2-af7cd7caeb3c (old id 151171)
date added to LUP
2007-06-27 11:15:01
date last changed
2017-01-01 04:53:42
@article{81a59a0d-2d2c-41b8-acd2-af7cd7caeb3c,
  abstract     = {An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel and liquid phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing play a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.},
  author       = {Marko-Varga, György and Nilsson, Johan and Laurell, Thomas},
  issn         = {0173-0835},
  keyword      = {Review,Biomarker,Miniaturization},
  language     = {eng},
  number       = {21-22},
  pages        = {3479--3491},
  publisher    = {John Wiley & Sons},
  series       = {Electrophoresis},
  title        = {New directions of miniaturization within the biomarker research area},
  url          = {http://dx.doi.org/10.1002/elps.200406109},
  volume       = {25},
  year         = {2004},
}