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Growth is dependent on the exocrine pancreas function in young weaners but not in growing-finishing pigs

Fedkiv, Olexandr LU ; Rengman, Sofia LU ; Weström, Björn LU and Pierzynowski, Stefan LU (2009) 6th International Symposium for Young Scientists - Human and Animal Development: Regulatory Mechanisms 60(Suppl. 3). p.55-59
Abstract
A correlation between the exocrine pancreatic function and growth has been previously demonstrated in growing pigs but the data are inconsistent. This was investigated by studying the growth performance of pigs with exocrine pancreatic insufficiency (EPI) at different ages and maintained under similar conditions. Twelve 7 week old (10.5 +/- 1.3 kg) weaners, and twelve 16 week old (43 +/- 5 kg) growing-finishing pigs were used in the experiments, and 6 pigs from each group were operated and pancreatic duct-ligated. Starting at 3-5 weeks after the operation, when EPI had developed, weekly recordings of feed consumption and growth were done before, during and after feed supplementation with porcine pancreatin (Creon (R) 10000). In weaner... (More)
A correlation between the exocrine pancreatic function and growth has been previously demonstrated in growing pigs but the data are inconsistent. This was investigated by studying the growth performance of pigs with exocrine pancreatic insufficiency (EPI) at different ages and maintained under similar conditions. Twelve 7 week old (10.5 +/- 1.3 kg) weaners, and twelve 16 week old (43 +/- 5 kg) growing-finishing pigs were used in the experiments, and 6 pigs from each group were operated and pancreatic duct-ligated. Starting at 3-5 weeks after the operation, when EPI had developed, weekly recordings of feed consumption and growth were done before, during and after feed supplementation with porcine pancreatin (Creon (R) 10000). In weaner pigs, EPI caused growth arrest while it did not affect the growth of older pigs, as compared to respective un-operated groups of pigs. The daily feed consumption (DFC) was lower in the weaner EPI-pigs while it was similar in the growing-finishing EPI-pigs, as compared to un-operated pigs. Feed supplementation with Creon (R) improved the DFC and growth in both the EPI and un-operated pigs. In conclusion, the results showed the importance of the exocrine pancreatic function for growth in weaner pigs, while in older animals it played a minor role in growth. Feed supplementation with pancreatin increased the appetite and ensured an improved feed conversion. (Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
procine pancreation, exocrine pancreas, age, growth, appetite
host publication
Journal of Physiology and Pharmacology
volume
60
issue
Suppl. 3
pages
55 - 59
publisher
Polish Physiological Society
conference name
6th International Symposium for Young Scientists - Human and Animal Development: Regulatory Mechanisms
conference location
Lublin, Poland
conference dates
2008-09-09 - 2008-09-10
external identifiers
  • wos:000271599500006
  • scopus:74549211798
ISSN
0867-5910
language
English
LU publication?
yes
id
a43eacb1-3d3c-4896-b39a-43e714f980ec (old id 1520036)
alternative location
http://www.jpp.krakow.pl/journal/archive/1009_s3/pdf/55_1009_s3_article.pdf
date added to LUP
2016-04-01 14:11:24
date last changed
2021-03-24 02:25:43
@inproceedings{a43eacb1-3d3c-4896-b39a-43e714f980ec,
  abstract     = {A correlation between the exocrine pancreatic function and growth has been previously demonstrated in growing pigs but the data are inconsistent. This was investigated by studying the growth performance of pigs with exocrine pancreatic insufficiency (EPI) at different ages and maintained under similar conditions. Twelve 7 week old (10.5 +/- 1.3 kg) weaners, and twelve 16 week old (43 +/- 5 kg) growing-finishing pigs were used in the experiments, and 6 pigs from each group were operated and pancreatic duct-ligated. Starting at 3-5 weeks after the operation, when EPI had developed, weekly recordings of feed consumption and growth were done before, during and after feed supplementation with porcine pancreatin (Creon (R) 10000). In weaner pigs, EPI caused growth arrest while it did not affect the growth of older pigs, as compared to respective un-operated groups of pigs. The daily feed consumption (DFC) was lower in the weaner EPI-pigs while it was similar in the growing-finishing EPI-pigs, as compared to un-operated pigs. Feed supplementation with Creon (R) improved the DFC and growth in both the EPI and un-operated pigs. In conclusion, the results showed the importance of the exocrine pancreatic function for growth in weaner pigs, while in older animals it played a minor role in growth. Feed supplementation with pancreatin increased the appetite and ensured an improved feed conversion.},
  author       = {Fedkiv, Olexandr and Rengman, Sofia and Weström, Björn and Pierzynowski, Stefan},
  booktitle    = {Journal of Physiology and Pharmacology},
  issn         = {0867-5910},
  language     = {eng},
  number       = {Suppl. 3},
  pages        = {55--59},
  publisher    = {Polish Physiological Society},
  title        = {Growth is dependent on the exocrine pancreas function in young weaners but not in growing-finishing pigs},
  url          = {http://www.jpp.krakow.pl/journal/archive/1009_s3/pdf/55_1009_s3_article.pdf},
  volume       = {60},
  year         = {2009},
}