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DNA compaction by cationic surfactant in solution and at polystyrene particle solution interfaces: a dynamic light scattering study

Cárdenas, Marité LU ; Schillén, Karin LU ; Nylander, Tommy LU ; Jansson, Jörgen LU and Lindman, Björn LU (2004) In Physical Chemistry Chemical Physics 6(7). p.1603-1607
Abstract
The effect of cationic surfactant on the compaction of DNA both in bulk solution and on polystyrene particles has been studied by dynamic light scattering. DNA undergoes a transition from a semiflexible coil to a more compact globule in aqueous solution as a consequence of cationic surfactant binding. Thus the hydrodynamic radius of DNA decreases from 107 nm to about 50 nm in the presence of cationic surfactant. Such compaction is also observed on DNA coated polystyrene particles. In this case, the hydrodynamic layer thickness of DNA coated particles is reduced from 36 to 5 nm in the presence of cetyltrimethylammonium bromide.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Chemistry Chemical Physics
volume
6
issue
7
pages
1603 - 1607
publisher
Royal Society of Chemistry
external identifiers
  • wos:000221222700051
  • scopus:19244371559
ISSN
1463-9084
DOI
10.1039/b310798a
language
English
LU publication?
yes
id
9f7e82da-367c-4d3c-b6ed-ad7e5bd34164 (old id 153758)
date added to LUP
2007-07-11 09:19:10
date last changed
2017-08-20 04:20:09
@article{9f7e82da-367c-4d3c-b6ed-ad7e5bd34164,
  abstract     = {The effect of cationic surfactant on the compaction of DNA both in bulk solution and on polystyrene particles has been studied by dynamic light scattering. DNA undergoes a transition from a semiflexible coil to a more compact globule in aqueous solution as a consequence of cationic surfactant binding. Thus the hydrodynamic radius of DNA decreases from 107 nm to about 50 nm in the presence of cationic surfactant. Such compaction is also observed on DNA coated polystyrene particles. In this case, the hydrodynamic layer thickness of DNA coated particles is reduced from 36 to 5 nm in the presence of cetyltrimethylammonium bromide.},
  author       = {Cárdenas, Marité and Schillén, Karin and Nylander, Tommy and Jansson, Jörgen and Lindman, Björn},
  issn         = {1463-9084},
  language     = {eng},
  number       = {7},
  pages        = {1603--1607},
  publisher    = {Royal Society of Chemistry},
  series       = {Physical Chemistry Chemical Physics},
  title        = {DNA compaction by cationic surfactant in solution and at polystyrene particle solution interfaces: a dynamic light scattering study},
  url          = {http://dx.doi.org/10.1039/b310798a},
  volume       = {6},
  year         = {2004},
}