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Treatment of local recurrences of giant cell tumour in long bones after curettage and cementing: A SCANDINAVIAN SARCOMA GROUP STUDY.

Vult von Steyern, Fredrik LU ; Bauer, H C F ; Trovik, C ; Kivioja, A ; Bergh, P ; Jorgensen, P Holmberg ; Folleras, G and Rydholm, Anders LU (2006) In Journal of Bone and Joint Surgery: British Volume 88(4). p.531-535
Abstract
We retrospectively studied local recurrence of giant cell tumour in long bones following treatment with curettage and cementing in 137 patients. The median follow-up time was 60 months (3 to 166). A total of 19 patients (14%) had at least one local recurrence, the first was diagnosed at a median of 17 months (3 to 29) after treatment of the primary tumour. There were 13 patients with a total of 15 local recurrences who were successfully treated by further curettage and cementing. Two patients with a second local recurrence were consequently treated twice. At the last follow-up, at a median of 53 months (3 to 128) after the most recent operation, all patients were free from disease and had good function. We concluded that local recurrence... (More)
We retrospectively studied local recurrence of giant cell tumour in long bones following treatment with curettage and cementing in 137 patients. The median follow-up time was 60 months (3 to 166). A total of 19 patients (14%) had at least one local recurrence, the first was diagnosed at a median of 17 months (3 to 29) after treatment of the primary tumour. There were 13 patients with a total of 15 local recurrences who were successfully treated by further curettage and cementing. Two patients with a second local recurrence were consequently treated twice. At the last follow-up, at a median of 53 months (3 to 128) after the most recent operation, all patients were free from disease and had good function. We concluded that local recurrence of giant cell tumour after curettage and cementing in long bones can generally be successfully treated with further curettage and cementing, with only a minor risk of increased morbidity. This suggests that more extensive surgery for the primary tumour in an attempt to obtain wide margins is not the method of choice, since it leaves the patient with higher morbidity with no significant gain with respect to cure of the disease. (Less)
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type
Contribution to journal
publication status
published
subject
in
Journal of Bone and Joint Surgery: British Volume
volume
88
issue
4
pages
531 - 535
publisher
British Editorial Society of Bone & Joint Surgery
external identifiers
  • pmid:16567792
  • wos:000237233500020
  • scopus:33646191218
  • pmid:16567792
ISSN
2044-5377
DOI
10.1302/0301-620X.88B4.17407
language
English
LU publication?
yes
id
f80b4bdf-cd80-4daa-9240-379a7f5a484e (old id 154346)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16567792&dopt=Abstract
date added to LUP
2016-04-01 12:12:01
date last changed
2020-12-15 01:37:32
@article{f80b4bdf-cd80-4daa-9240-379a7f5a484e,
  abstract     = {We retrospectively studied local recurrence of giant cell tumour in long bones following treatment with curettage and cementing in 137 patients. The median follow-up time was 60 months (3 to 166). A total of 19 patients (14%) had at least one local recurrence, the first was diagnosed at a median of 17 months (3 to 29) after treatment of the primary tumour. There were 13 patients with a total of 15 local recurrences who were successfully treated by further curettage and cementing. Two patients with a second local recurrence were consequently treated twice. At the last follow-up, at a median of 53 months (3 to 128) after the most recent operation, all patients were free from disease and had good function. We concluded that local recurrence of giant cell tumour after curettage and cementing in long bones can generally be successfully treated with further curettage and cementing, with only a minor risk of increased morbidity. This suggests that more extensive surgery for the primary tumour in an attempt to obtain wide margins is not the method of choice, since it leaves the patient with higher morbidity with no significant gain with respect to cure of the disease.},
  author       = {Vult von Steyern, Fredrik and Bauer, H C F and Trovik, C and Kivioja, A and Bergh, P and Jorgensen, P Holmberg and Folleras, G and Rydholm, Anders},
  issn         = {2044-5377},
  language     = {eng},
  number       = {4},
  pages        = {531--535},
  publisher    = {British Editorial Society of Bone & Joint Surgery},
  series       = {Journal of Bone and Joint Surgery: British Volume},
  title        = {Treatment of local recurrences of giant cell tumour in long bones after curettage and cementing: A SCANDINAVIAN SARCOMA GROUP STUDY.},
  url          = {http://dx.doi.org/10.1302/0301-620X.88B4.17407},
  doi          = {10.1302/0301-620X.88B4.17407},
  volume       = {88},
  year         = {2006},
}