Can active sun exposure decrease the risk of giant cell arteritis and polymyalgia rheumatica in women?
Gisslander, Karl LU
; de Boer, Raïssa
LU
; Ingvar, Christian
LU
; Turesson, Carl
LU
; Isaksson, Karolin
LU
; Jayne, David
and Mohammad, Aladdin
LU
(2023)
In Rheumatology Advances in Practice
7(3).
- Abstract
- Objectives
To study if active sun exposure among women affects the risk of developing GCA or PMR in a prospective cohort study with restricted latitudinal variability.
Methods
We linked the response to questions relating to sun exposure from the Melanoma Inquiry in Southern Sweden (MISS) prospective cohort study in women to the risk of developing GCA or PMR. Healthcare data were gathered from the Skåne Healthcare Register (SHR), covering all public healthcare consultations. The direct effect of active sun exposure on the risk of developing GCA or PMR was assessed using Cox proportional hazards models adjusted for covariates based on a directed acyclic graph.
Results
A total of 14 574 women were included... (More) - Objectives
To study if active sun exposure among women affects the risk of developing GCA or PMR in a prospective cohort study with restricted latitudinal variability.
Methods
We linked the response to questions relating to sun exposure from the Melanoma Inquiry in Southern Sweden (MISS) prospective cohort study in women to the risk of developing GCA or PMR. Healthcare data were gathered from the Skåne Healthcare Register (SHR), covering all public healthcare consultations. The direct effect of active sun exposure on the risk of developing GCA or PMR was assessed using Cox proportional hazards models adjusted for covariates based on a directed acyclic graph.
Results
A total of 14 574 women were included in the study; 601 women were diagnosed with GCA or PMR (144 and 457, respectively) during the follow-up time. Women with moderate or high sun exposure were not less likely to develop GCA or PMR compared with women that indicated they avoided sun exposure [hazard ratio (HR) 1.2 (CI 0.9, 1.6) and 1.3 (0.9, 1.9), respectively] when adjusted for diabetes, hyperlipidaemia, hypertension, smoking, obesity and stratified by age. Similar patterns were observed when studying only GCA [HR 1.2 (CI 0.7, 2.3) and 1.3 (0.7, 2.6)] and only PMR [HR 1.3 (CI 0.9, 1.8) and 1.4 (0.9, 2.0)].
Conclusion
Active sun exposure did not affect the risk of developing GCA or PMR in women in a cohort with restricted latitudinal variability. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/154d9dbd-697c-480e-9d3e-282fdbd7ed89
- author
- Gisslander, Karl
LU
; de Boer, Raïssa
LU
; Ingvar, Christian
LU
; Turesson, Carl
LU
; Isaksson, Karolin
LU
; Jayne, David
and Mohammad, Aladdin
LU
- organization
- publishing date
- 2023-08-18
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Rheumatology Advances in Practice
- volume
- 7
- issue
- 3
- publisher
- Oxford University Press
- external identifiers
-
- scopus:85172211040
- pmid:37675201
- ISSN
- 2514-1775
- DOI
- 10.1093/rap/rkad071
- language
- English
- LU publication?
- yes
- id
- 154d9dbd-697c-480e-9d3e-282fdbd7ed89
- date added to LUP
- 2023-10-06 09:13:51
- date last changed
- 2024-01-09 15:45:55
@article{154d9dbd-697c-480e-9d3e-282fdbd7ed89,
abstract = {{Objectives<br/><br/>To study if active sun exposure among women affects the risk of developing GCA or PMR in a prospective cohort study with restricted latitudinal variability.<br/><br/>Methods<br/>We linked the response to questions relating to sun exposure from the Melanoma Inquiry in Southern Sweden (MISS) prospective cohort study in women to the risk of developing GCA or PMR. Healthcare data were gathered from the Skåne Healthcare Register (SHR), covering all public healthcare consultations. The direct effect of active sun exposure on the risk of developing GCA or PMR was assessed using Cox proportional hazards models adjusted for covariates based on a directed acyclic graph.<br/><br/>Results<br/>A total of 14 574 women were included in the study; 601 women were diagnosed with GCA or PMR (144 and 457, respectively) during the follow-up time. Women with moderate or high sun exposure were not less likely to develop GCA or PMR compared with women that indicated they avoided sun exposure [hazard ratio (HR) 1.2 (CI 0.9, 1.6) and 1.3 (0.9, 1.9), respectively] when adjusted for diabetes, hyperlipidaemia, hypertension, smoking, obesity and stratified by age. Similar patterns were observed when studying only GCA [HR 1.2 (CI 0.7, 2.3) and 1.3 (0.7, 2.6)] and only PMR [HR 1.3 (CI 0.9, 1.8) and 1.4 (0.9, 2.0)].<br/><br/>Conclusion<br/>Active sun exposure did not affect the risk of developing GCA or PMR in women in a cohort with restricted latitudinal variability.}},
author = {{Gisslander, Karl and de Boer, Raïssa and Ingvar, Christian and Turesson, Carl and Isaksson, Karolin and Jayne, David and Mohammad, Aladdin}},
issn = {{2514-1775}},
language = {{eng}},
month = {{08}},
number = {{3}},
publisher = {{Oxford University Press}},
series = {{Rheumatology Advances in Practice}},
title = {{Can active sun exposure decrease the risk of giant cell arteritis and polymyalgia rheumatica in women?}},
url = {{http://dx.doi.org/10.1093/rap/rkad071}},
doi = {{10.1093/rap/rkad071}},
volume = {{7}},
year = {{2023}},
}