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Extraction of rosavin from Rhodiola rosea root using supercritical carbon dioxide with water

Iheozor-Ejidor, Pamela and Dey, Estera LU (2009) In Journal of Supercritical Fluids 50(1). p.29-32
Abstract
In this study, a new extraction method for the isolation of rosavin from dried crushed roots of Rhodiola rosea is being developed using supercritical CO2 and water. Rosavin extracts quantitatively and qualitatively were compared to commonly used solvents such as methanol, ethanol and ethyl acetate. By HPLC analysis rosavin was found to be the dominant compound in extracts obtained by both extraction methods. Quantitative differences were observed between the two extraction methods. Among the solvents, methanol yielded 3.3% while ethanol only 1.2% of rosavin. Supercritical CO2 and water at extraction temperature 80 degrees C and 5 h yielded 4.5% of rosavin. (C) 2009 Elsevier B.V. All rights reserved.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
dioxide (scCO(2)) with water, Supercritical carbon, Bioactive substances, Rhodiola rosea, Rosavin, Solvents, Extraction, HPLC
in
Journal of Supercritical Fluids
volume
50
issue
1
pages
29 - 32
publisher
Elsevier
external identifiers
  • wos:000274354700005
  • scopus:67349090590
ISSN
0896-8446
DOI
10.1016/j.supflu.2009.04.011
language
English
LU publication?
yes
id
916fc3b2-6932-457c-83bf-30389f61c3ce (old id 1567804)
date added to LUP
2010-03-24 13:18:01
date last changed
2017-08-27 03:56:00
@article{916fc3b2-6932-457c-83bf-30389f61c3ce,
  abstract     = {In this study, a new extraction method for the isolation of rosavin from dried crushed roots of Rhodiola rosea is being developed using supercritical CO2 and water. Rosavin extracts quantitatively and qualitatively were compared to commonly used solvents such as methanol, ethanol and ethyl acetate. By HPLC analysis rosavin was found to be the dominant compound in extracts obtained by both extraction methods. Quantitative differences were observed between the two extraction methods. Among the solvents, methanol yielded 3.3% while ethanol only 1.2% of rosavin. Supercritical CO2 and water at extraction temperature 80 degrees C and 5 h yielded 4.5% of rosavin. (C) 2009 Elsevier B.V. All rights reserved.},
  author       = {Iheozor-Ejidor, Pamela and Dey, Estera},
  issn         = {0896-8446},
  keyword      = {dioxide (scCO(2)) with water,Supercritical carbon,Bioactive substances,Rhodiola rosea,Rosavin,Solvents,Extraction,HPLC},
  language     = {eng},
  number       = {1},
  pages        = {29--32},
  publisher    = {Elsevier},
  series       = {Journal of Supercritical Fluids},
  title        = {Extraction of rosavin from Rhodiola rosea root using supercritical carbon dioxide with water},
  url          = {http://dx.doi.org/10.1016/j.supflu.2009.04.011},
  volume       = {50},
  year         = {2009},
}