Trisomy 8 as the sole chromosomal aberration in acute myeloid leukemia and myelodysplastic syndromes.
(2007) In Pathologie Biologie 55(1). p.37-48- Abstract
- Trisomy 8 as the sole abnormality is the most common karyotypic finding in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), occurring in approximately 5% and 10% of the cytogenetically abnormal cases, respectively. However, despite the high frequency of +8, much remains to be elucidated as regards its epidemiology, etiology, clinical impact, association with other chromosomal abnormalities, cell of origin, and functional and pathogenetic consequences. Here, we summarize and review these various aspects of trisomy 8, focusing on AMLs and MDS harboring this abnormality as a single change.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/156811
- author
- Paulsson, Kajsa LU and Johansson, Bertil LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- sole, trisomy 8, acute myeloid leukemia, chromosomal aberration, myelodysplastic syndrome
- in
- Pathologie Biologie
- volume
- 55
- issue
- 1
- pages
- 37 - 48
- publisher
- Elsevier
- external identifiers
-
- wos:000244914600005
- scopus:33846853947
- ISSN
- 0369-8114
- DOI
- 10.1016/j.patbio.2006.04.007
- language
- English
- LU publication?
- yes
- id
- 1d401e8c-b879-476a-8b61-45cc69fe4992 (old id 156811)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16697122&dopt=Abstract
- date added to LUP
- 2016-04-01 15:24:36
- date last changed
- 2022-03-22 04:17:45
@article{1d401e8c-b879-476a-8b61-45cc69fe4992, abstract = {{Trisomy 8 as the sole abnormality is the most common karyotypic finding in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), occurring in approximately 5% and 10% of the cytogenetically abnormal cases, respectively. However, despite the high frequency of +8, much remains to be elucidated as regards its epidemiology, etiology, clinical impact, association with other chromosomal abnormalities, cell of origin, and functional and pathogenetic consequences. Here, we summarize and review these various aspects of trisomy 8, focusing on AMLs and MDS harboring this abnormality as a single change.}}, author = {{Paulsson, Kajsa and Johansson, Bertil}}, issn = {{0369-8114}}, keywords = {{sole; trisomy 8; acute myeloid leukemia; chromosomal aberration; myelodysplastic syndrome}}, language = {{eng}}, number = {{1}}, pages = {{37--48}}, publisher = {{Elsevier}}, series = {{Pathologie Biologie}}, title = {{Trisomy 8 as the sole chromosomal aberration in acute myeloid leukemia and myelodysplastic syndromes.}}, url = {{https://lup.lub.lu.se/search/files/4385983/625464.pdf}}, doi = {{10.1016/j.patbio.2006.04.007}}, volume = {{55}}, year = {{2007}}, }