The incidence of spina bifida in Sweden 1973-2003: the effect of prenatal diagnosis.
(2006) In European Journal of Public Health 16(6). p.660-662- Abstract
- Background: Many studies have been conducted on the accuracy of prenatal ultrasound diagnosis of foetal CNS-malformations. These studies were mostly hospital-based or, sometimes, multicentre studies. We present here a population-based study of the prenatal diagnosis of spina bifida in Sweden over a period of 31 years. Methods: We compared the number of newborns with spina bifida and the elective terminations because of the prenatal diagnosis of spina bifida for different periods. Results: The rate of spina bifida among newborns diminished gradually from 0.55 per 1000 to 0.29 per 1000 during the study period. In M county the rate of spina bifida at birth decreased very rapidly and from 1993 onwards was about half of that in the rest of the... (More)
- Background: Many studies have been conducted on the accuracy of prenatal ultrasound diagnosis of foetal CNS-malformations. These studies were mostly hospital-based or, sometimes, multicentre studies. We present here a population-based study of the prenatal diagnosis of spina bifida in Sweden over a period of 31 years. Methods: We compared the number of newborns with spina bifida and the elective terminations because of the prenatal diagnosis of spina bifida for different periods. Results: The rate of spina bifida among newborns diminished gradually from 0.55 per 1000 to 0.29 per 1000 during the study period. In M county the rate of spina bifida at birth decreased very rapidly and from 1993 onwards was about half of that in the rest of the country. Conclusion: There has been a decline in the rate of spina bifida at birth. This decline can be seen earlier in the southern part of the country, M county. The decline is probably, to a great extent, a consequence of prenatal ultrasound screening. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/157070
- author
- Nikkilä, Annamari LU ; Rydhstrom, Hakan and Källén, Bengt LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- ultrasound screening, spina bifida, prenatal diagnosis
- in
- European Journal of Public Health
- volume
- 16
- issue
- 6
- pages
- 660 - 662
- publisher
- Oxford University Press
- external identifiers
-
- wos:000242472500019
- scopus:33845453794
- pmid:16672253
- ISSN
- 1101-1262
- DOI
- 10.1093/eurpub/ckl053
- language
- English
- LU publication?
- yes
- id
- a5419c1e-0ed7-46e6-a377-53d85511fd05 (old id 157070)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16672253&dopt=Abstract
- date added to LUP
- 2016-04-01 12:08:11
- date last changed
- 2022-01-26 23:19:38
@article{a5419c1e-0ed7-46e6-a377-53d85511fd05,
abstract = {{Background: Many studies have been conducted on the accuracy of prenatal ultrasound diagnosis of foetal CNS-malformations. These studies were mostly hospital-based or, sometimes, multicentre studies. We present here a population-based study of the prenatal diagnosis of spina bifida in Sweden over a period of 31 years. Methods: We compared the number of newborns with spina bifida and the elective terminations because of the prenatal diagnosis of spina bifida for different periods. Results: The rate of spina bifida among newborns diminished gradually from 0.55 per 1000 to 0.29 per 1000 during the study period. In M county the rate of spina bifida at birth decreased very rapidly and from 1993 onwards was about half of that in the rest of the country. Conclusion: There has been a decline in the rate of spina bifida at birth. This decline can be seen earlier in the southern part of the country, M county. The decline is probably, to a great extent, a consequence of prenatal ultrasound screening.}},
author = {{Nikkilä, Annamari and Rydhstrom, Hakan and Källén, Bengt}},
issn = {{1101-1262}},
keywords = {{ultrasound screening; spina bifida; prenatal diagnosis}},
language = {{eng}},
number = {{6}},
pages = {{660--662}},
publisher = {{Oxford University Press}},
series = {{European Journal of Public Health}},
title = {{The incidence of spina bifida in Sweden 1973-2003: the effect of prenatal diagnosis.}},
url = {{http://dx.doi.org/10.1093/eurpub/ckl053}},
doi = {{10.1093/eurpub/ckl053}},
volume = {{16}},
year = {{2006}},
}