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DNA compaction onto hydrophobic surfaces by different cationic surfactants

Cárdenas, Marité LU ; Nylander, Tommy LU ; Thomas, R K and Lindman, Björn LU (2005) In Langmuir 21(14). p.6495-6502
Abstract
DNA compaction by alkyltrimethylammonium surfactants at hydrophobized silica surfaces and the effect of the counterion, as well as the hydrocarbon chain length, was investigated by in situ null-ellipsometry. In addition, DNA compaction in the presence of a gemini surfactant, hexyl-alpha,omega-bis(dodecyldimethylammonium bromide), was studied. The type of cationic amphiphile used was found not to have a pronounced effect on the mixed DNA-cationic surfactant adsorbed layer thickness, although the surface concentration excess for the mixed layers seemed to follow the same trend as that for DNA-free surfactant layers. Interestingly, it was also found that the stability of the mixed adsorbed layer largely depends on the cationic surfactant used.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Langmuir
volume
21
issue
14
pages
6495 - 6502
publisher
The American Chemical Society
external identifiers
  • wos:000230248500052
  • pmid:15982058
  • scopus:22444439152
ISSN
0743-7463
DOI
10.1021/la0501740
language
English
LU publication?
yes
id
f5bcc647-cfd6-4882-aa6e-1eea545c8f30 (old id 157259)
date added to LUP
2007-07-11 08:42:15
date last changed
2017-01-01 05:00:28
@article{f5bcc647-cfd6-4882-aa6e-1eea545c8f30,
  abstract     = {DNA compaction by alkyltrimethylammonium surfactants at hydrophobized silica surfaces and the effect of the counterion, as well as the hydrocarbon chain length, was investigated by in situ null-ellipsometry. In addition, DNA compaction in the presence of a gemini surfactant, hexyl-alpha,omega-bis(dodecyldimethylammonium bromide), was studied. The type of cationic amphiphile used was found not to have a pronounced effect on the mixed DNA-cationic surfactant adsorbed layer thickness, although the surface concentration excess for the mixed layers seemed to follow the same trend as that for DNA-free surfactant layers. Interestingly, it was also found that the stability of the mixed adsorbed layer largely depends on the cationic surfactant used.},
  author       = {Cárdenas, Marité and Nylander, Tommy and Thomas, R K and Lindman, Björn},
  issn         = {0743-7463},
  language     = {eng},
  number       = {14},
  pages        = {6495--6502},
  publisher    = {The American Chemical Society},
  series       = {Langmuir},
  title        = {DNA compaction onto hydrophobic surfaces by different cationic surfactants},
  url          = {http://dx.doi.org/10.1021/la0501740},
  volume       = {21},
  year         = {2005},
}