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Serum selenium concentrations in patients with autoimmune thyroiditis and non-toxic nodular goiter

Ericsson, U B ; Erfurth, E M LU and Schütz, A LU (1993) In Thyroidology 5(1). p.4-21
Abstract

Selenium (Se) deficiency is said to contribute to the atrophy of the thyroid gland in certain endemic goiter areas in Africa. To test the hypothesis that, a low Se intake could protect against goiter development in autoimmune thyroiditis, we analysed the Se concentration in 20 patients with the atrophic variant of lymphocytic thyroiditis, 23 patients with Hashimoto's thyroiditis and 23 patients with non-toxic nodular (colloid) goiter. Twenty healthy females served as controls. We did not find any significant difference in serum selenium (S-Se) levels between the patients with the various thyroid disorders or between patients and controls. There was no difference in the S-Se concentration and the triiodothyronine (T3), thyroxine (T4),... (More)

Selenium (Se) deficiency is said to contribute to the atrophy of the thyroid gland in certain endemic goiter areas in Africa. To test the hypothesis that, a low Se intake could protect against goiter development in autoimmune thyroiditis, we analysed the Se concentration in 20 patients with the atrophic variant of lymphocytic thyroiditis, 23 patients with Hashimoto's thyroiditis and 23 patients with non-toxic nodular (colloid) goiter. Twenty healthy females served as controls. We did not find any significant difference in serum selenium (S-Se) levels between the patients with the various thyroid disorders or between patients and controls. There was no difference in the S-Se concentration and the triiodothyronine (T3), thyroxine (T4), thyrotropin (TSH) or thyroglobulin concentrations in serum. Thus, the Se status had no impact on the development of goiter.

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author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Female, Goiter, Nodular/blood, Humans, Male, Middle Aged, Selenium/blood, Thyroiditis, Autoimmune/blood, Thyrotropin/blood, Thyroxine/blood, Triiodothyronine/blood
in
Thyroidology
volume
5
issue
1
pages
4 - 21
publisher
Pacini Editore s.r.l.
external identifiers
  • scopus:0027573277
  • pmid:7508739
ISSN
1121-7596
language
English
LU publication?
no
id
1589bfc6-2ed7-4828-b008-b7a3d7be51e4
date added to LUP
2023-11-27 09:52:00
date last changed
2024-01-10 11:53:00
@article{1589bfc6-2ed7-4828-b008-b7a3d7be51e4,
  abstract     = {{<p>Selenium (Se) deficiency is said to contribute to the atrophy of the thyroid gland in certain endemic goiter areas in Africa. To test the hypothesis that, a low Se intake could protect against goiter development in autoimmune thyroiditis, we analysed the Se concentration in 20 patients with the atrophic variant of lymphocytic thyroiditis, 23 patients with Hashimoto's thyroiditis and 23 patients with non-toxic nodular (colloid) goiter. Twenty healthy females served as controls. We did not find any significant difference in serum selenium (S-Se) levels between the patients with the various thyroid disorders or between patients and controls. There was no difference in the S-Se concentration and the triiodothyronine (T3), thyroxine (T4), thyrotropin (TSH) or thyroglobulin concentrations in serum. Thus, the Se status had no impact on the development of goiter.</p>}},
  author       = {{Ericsson, U B and Erfurth, E M and Schütz, A}},
  issn         = {{1121-7596}},
  keywords     = {{Adult; Female; Goiter, Nodular/blood; Humans; Male; Middle Aged; Selenium/blood; Thyroiditis, Autoimmune/blood; Thyrotropin/blood; Thyroxine/blood; Triiodothyronine/blood}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{4--21}},
  publisher    = {{Pacini Editore s.r.l.}},
  series       = {{Thyroidology}},
  title        = {{Serum selenium concentrations in patients with autoimmune thyroiditis and non-toxic nodular goiter}},
  volume       = {{5}},
  year         = {{1993}},
}