Influence of Salt on the Self-Assembly of Two Model Amyloid Heptapeptides
(2010) In The Journal of Physical Chemistry Part B 114(23). p.8002-8008- Abstract
- We study the effects of NaCl on the self-assembly of AAKLVFF and beta A beta AKLVFF in solution. Both AAKLVFF and beta A beta AKLVFF self-assemble into twisted fibers in aqueous solution. The addition of NaCl to aqueous solutions of AAKLVFF produces large crystal-like nanotapes which eventually precipitate. In contrast, highly twisted fibrils were observed for beta A beta AKLVFF solutions at low salt concentration, while a coexistence of highly twisted fibers and nanotubes was observed for beta A beta AKLVFF at high salt concentration. The self-assembled structures observed for beta A beta AKLVFF in NaCl solutions were ascribed to the progressive screening of the beta A beta AKLVFF surface charge caused by the addition of salt.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1630957
- author
- Castelletto, V. ; Hamley, I. W. ; Cenker, Celen LU and Olsson, Ulf LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- The Journal of Physical Chemistry Part B
- volume
- 114
- issue
- 23
- pages
- 8002 - 8008
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000278479900035
- scopus:77953420989
- pmid:20496898
- ISSN
- 1520-5207
- DOI
- 10.1021/jp102744g
- language
- English
- LU publication?
- yes
- id
- c22f34ed-ea33-4a94-a0c3-66d231df34b7 (old id 1630957)
- date added to LUP
- 2016-04-01 12:51:29
- date last changed
- 2022-04-06 01:10:57
@article{c22f34ed-ea33-4a94-a0c3-66d231df34b7, abstract = {{We study the effects of NaCl on the self-assembly of AAKLVFF and beta A beta AKLVFF in solution. Both AAKLVFF and beta A beta AKLVFF self-assemble into twisted fibers in aqueous solution. The addition of NaCl to aqueous solutions of AAKLVFF produces large crystal-like nanotapes which eventually precipitate. In contrast, highly twisted fibrils were observed for beta A beta AKLVFF solutions at low salt concentration, while a coexistence of highly twisted fibers and nanotubes was observed for beta A beta AKLVFF at high salt concentration. The self-assembled structures observed for beta A beta AKLVFF in NaCl solutions were ascribed to the progressive screening of the beta A beta AKLVFF surface charge caused by the addition of salt.}}, author = {{Castelletto, V. and Hamley, I. W. and Cenker, Celen and Olsson, Ulf}}, issn = {{1520-5207}}, language = {{eng}}, number = {{23}}, pages = {{8002--8008}}, publisher = {{The American Chemical Society (ACS)}}, series = {{The Journal of Physical Chemistry Part B}}, title = {{Influence of Salt on the Self-Assembly of Two Model Amyloid Heptapeptides}}, url = {{http://dx.doi.org/10.1021/jp102744g}}, doi = {{10.1021/jp102744g}}, volume = {{114}}, year = {{2010}}, }