Does supervised exercise after deep venous thrombosis improve recanalization of occluded vein segments? A randomized study.
(2007) In Journal of Thrombosis and Thrombolysis 23(1). p.25-30- Abstract
- Objectives The aim of the present study was to evaluate weather early supervised exercise improves recanalization of acute deep vein thrombosis (DVT) and reduces symptoms. Patients and methods From September 2001 to March 2004, of 381 patients, 72 eligible patients were included and with a mean age 54 +/- 14 years, 39 (52%) men with deep vein thrombosis ( DVT) proven with phlebography were randomized to: an exercise group (n = 36) receiving routine anticoagulation, class II compression stockings and additionally supervised exercise and a control group ( n = 36) receiving the same therapy but no exercise. Patients were followed-up during six months. Phlebography was scored initially and at six-months. Results There were at inclusion no... (More)
- Objectives The aim of the present study was to evaluate weather early supervised exercise improves recanalization of acute deep vein thrombosis (DVT) and reduces symptoms. Patients and methods From September 2001 to March 2004, of 381 patients, 72 eligible patients were included and with a mean age 54 +/- 14 years, 39 (52%) men with deep vein thrombosis ( DVT) proven with phlebography were randomized to: an exercise group (n = 36) receiving routine anticoagulation, class II compression stockings and additionally supervised exercise and a control group ( n = 36) receiving the same therapy but no exercise. Patients were followed-up during six months. Phlebography was scored initially and at six-months. Results There were at inclusion no differences between the two groups regarding age, body weight, body mass index (BMI), calf circumference of the affected leg, and overall quality of life estimated by visual analog scale ( VAS)-scale. In both groups there were significant reductions regarding calf circumference in the affected leg compared to the inclusion time, both at one-month ( P = 0.0012) and six month ( P = 0.0002) follow-up. The degree of recanalization of the affected venous segments was high and did not differ between groups. There were no recurrent DVT or pulmonary emboli or other treatment complications in any individual during the six-month follow-up period. Conclusions Early exercise did not acutely exacerbate the risk of complications in patients with DVT. No benefits of early exercise were seen regarding the degree of recanalization of the thrombi, or faster resolution of pain or swelling. Nevertheless, our study shows that early exercise/ambulation is safe in combination with anticoagulation and compression stockings for the majority of patients with DVT. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/163799
- author
- Isma, Nazim LU ; Johanssson, Ellinor ; Bjork, Anna ; Björgell, Ola LU ; Robertson, Fredrik LU ; Mattiasson, Ingrid LU ; Gottsäter, Anders LU and Lindblad, Bengt LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- recanalization, thrombosis, outpatient management, DVT, exercise/ambulation
- in
- Journal of Thrombosis and Thrombolysis
- volume
- 23
- issue
- 1
- pages
- 25 - 30
- publisher
- Springer
- external identifiers
-
- wos:000244199500003
- scopus:33846980830
- ISSN
- 1573-742X
- DOI
- 10.1007/s11239-006-9010-y
- language
- English
- LU publication?
- yes
- id
- e4047fb0-7f2d-4284-912f-efdb78922fee (old id 163799)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17186396&dopt=Abstract
- date added to LUP
- 2016-04-01 16:10:47
- date last changed
- 2022-02-12 20:20:26
@article{e4047fb0-7f2d-4284-912f-efdb78922fee,
abstract = {{Objectives The aim of the present study was to evaluate weather early supervised exercise improves recanalization of acute deep vein thrombosis (DVT) and reduces symptoms. Patients and methods From September 2001 to March 2004, of 381 patients, 72 eligible patients were included and with a mean age 54 +/- 14 years, 39 (52%) men with deep vein thrombosis ( DVT) proven with phlebography were randomized to: an exercise group (n = 36) receiving routine anticoagulation, class II compression stockings and additionally supervised exercise and a control group ( n = 36) receiving the same therapy but no exercise. Patients were followed-up during six months. Phlebography was scored initially and at six-months. Results There were at inclusion no differences between the two groups regarding age, body weight, body mass index (BMI), calf circumference of the affected leg, and overall quality of life estimated by visual analog scale ( VAS)-scale. In both groups there were significant reductions regarding calf circumference in the affected leg compared to the inclusion time, both at one-month ( P = 0.0012) and six month ( P = 0.0002) follow-up. The degree of recanalization of the affected venous segments was high and did not differ between groups. There were no recurrent DVT or pulmonary emboli or other treatment complications in any individual during the six-month follow-up period. Conclusions Early exercise did not acutely exacerbate the risk of complications in patients with DVT. No benefits of early exercise were seen regarding the degree of recanalization of the thrombi, or faster resolution of pain or swelling. Nevertheless, our study shows that early exercise/ambulation is safe in combination with anticoagulation and compression stockings for the majority of patients with DVT.}},
author = {{Isma, Nazim and Johanssson, Ellinor and Bjork, Anna and Björgell, Ola and Robertson, Fredrik and Mattiasson, Ingrid and Gottsäter, Anders and Lindblad, Bengt}},
issn = {{1573-742X}},
keywords = {{recanalization; thrombosis; outpatient management; DVT; exercise/ambulation}},
language = {{eng}},
number = {{1}},
pages = {{25--30}},
publisher = {{Springer}},
series = {{Journal of Thrombosis and Thrombolysis}},
title = {{Does supervised exercise after deep venous thrombosis improve recanalization of occluded vein segments? A randomized study.}},
url = {{https://lup.lub.lu.se/search/files/4593462/625797.pdf}},
doi = {{10.1007/s11239-006-9010-y}},
volume = {{23}},
year = {{2007}},
}