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Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease.

Thorlacius, Henrik LU and Toth, Ervin LU (2007) In Inflammatory Bowel Diseases 13(7). p.911-917
Abstract
Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. However, it is now generally accepted that neoplastic changes in colitis are frequently flat and depressed, which are easily missed by use of routine colonoscopy. The introduction of chromoendoscopy, especially in combination with magnifying endoscopy, has greatly advanced our means to detect and differentiate neoplastic lesions in the colorectum.... (More)
Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. However, it is now generally accepted that neoplastic changes in colitis are frequently flat and depressed, which are easily missed by use of routine colonoscopy. The introduction of chromoendoscopy, especially in combination with magnifying endoscopy, has greatly advanced our means to detect and differentiate neoplastic lesions in the colorectum. Accumulating evidence-based data indicate that implementation of chromoendoscopy into colon cancer surveillance protocols for patients with inflammatory bowel disease is effective. However, the introduction of chromoendoscopy into surveillance programs requires meticulous training and further studies to compare the value of chromoendoscopy to newer endoscopic devices and techniques, such as narrow band imaging. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cancer, colonoscopy, colon, chromoendoscopy, IBD, surveillance
in
Inflammatory Bowel Diseases
volume
13
issue
7
pages
911 - 917
publisher
John Wiley & Sons
external identifiers
  • wos:000247784800012
  • scopus:34547631779
ISSN
1536-4844
DOI
10.1002/ibd.20118
language
English
LU publication?
yes
id
f6dc5f11-a21a-4c16-a845-9137a4060c05 (old id 165606)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17309075&dopt=Abstract
date added to LUP
2007-07-30 16:05:54
date last changed
2017-07-23 03:54:19
@article{f6dc5f11-a21a-4c16-a845-9137a4060c05,
  abstract     = {Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. However, it is now generally accepted that neoplastic changes in colitis are frequently flat and depressed, which are easily missed by use of routine colonoscopy. The introduction of chromoendoscopy, especially in combination with magnifying endoscopy, has greatly advanced our means to detect and differentiate neoplastic lesions in the colorectum. Accumulating evidence-based data indicate that implementation of chromoendoscopy into colon cancer surveillance protocols for patients with inflammatory bowel disease is effective. However, the introduction of chromoendoscopy into surveillance programs requires meticulous training and further studies to compare the value of chromoendoscopy to newer endoscopic devices and techniques, such as narrow band imaging.},
  author       = {Thorlacius, Henrik and Toth, Ervin},
  issn         = {1536-4844},
  keyword      = {cancer,colonoscopy,colon,chromoendoscopy,IBD,surveillance},
  language     = {eng},
  number       = {7},
  pages        = {911--917},
  publisher    = {John Wiley & Sons},
  series       = {Inflammatory Bowel Diseases},
  title        = {Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease.},
  url          = {http://dx.doi.org/10.1002/ibd.20118},
  volume       = {13},
  year         = {2007},
}