Bacterial aetiology in ventilator-associated pneumonia at a Swedish university hospital
(2010) In Scandinavian Journal of Infectious Diseases 42(6-7). p.469-474- Abstract
- Ventilator-associated pneumonia (VAP) is a common complication of respiratory support and is associated with increased mortality, morbidity and costs, and a prolonged stay in the intensive care unit. Scandinavian data on the aetiology in VAP are lacking. We hereby present a retrospective study on the aetiology of VAP diagnosed by protective specimen brush culture at Malmo University Hospital in relation to early-and late-onset VAP, antibiotic treatment and the incidence of drug-resistant bacteria. Patients registered with a diagnosis of VAP between January 2004 and September 2007 were included in the study. Sixty-five of 109 patients diagnosed with VAP met the inclusion criteria, and 103 bacterial isolates were cultured from these... (More)
- Ventilator-associated pneumonia (VAP) is a common complication of respiratory support and is associated with increased mortality, morbidity and costs, and a prolonged stay in the intensive care unit. Scandinavian data on the aetiology in VAP are lacking. We hereby present a retrospective study on the aetiology of VAP diagnosed by protective specimen brush culture at Malmo University Hospital in relation to early-and late-onset VAP, antibiotic treatment and the incidence of drug-resistant bacteria. Patients registered with a diagnosis of VAP between January 2004 and September 2007 were included in the study. Sixty-five of 109 patients diagnosed with VAP met the inclusion criteria, and 103 bacterial isolates were cultured from these patients. The most common findings among the 65 VAP episodes were Enterobacteriaceae (28), Pseudomonas aeruginosa (13), Haemophilus influenzae (12) and Staphylococcus aureus (8). Patients with no antibiotic treatment at the onset of VAP had significantly more H. influenzae (p = 0.035) and Gram-positive pathogenic bacteria (p = 0.019). There was no difference in incidence of P. aeruginosa between early-and late-onset VAP. Resistant bacteria were found in 18% of the patients. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1656925
- author
- Ahl, Jonas LU ; Tham, Johan LU ; Walder, Mats LU ; Melander, Eva LU and Odenholt, Inga LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 42
- issue
- 6-7
- pages
- 469 - 474
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000279896500011
- scopus:77953251960
- pmid:20370356
- ISSN
- 1651-1980
- DOI
- 10.3109/00365541003621494
- language
- English
- LU publication?
- yes
- id
- 51b3bc78-417a-451c-a188-b09308f69e90 (old id 1656925)
- date added to LUP
- 2016-04-01 13:59:50
- date last changed
- 2022-01-27 22:17:00
@article{51b3bc78-417a-451c-a188-b09308f69e90, abstract = {{Ventilator-associated pneumonia (VAP) is a common complication of respiratory support and is associated with increased mortality, morbidity and costs, and a prolonged stay in the intensive care unit. Scandinavian data on the aetiology in VAP are lacking. We hereby present a retrospective study on the aetiology of VAP diagnosed by protective specimen brush culture at Malmo University Hospital in relation to early-and late-onset VAP, antibiotic treatment and the incidence of drug-resistant bacteria. Patients registered with a diagnosis of VAP between January 2004 and September 2007 were included in the study. Sixty-five of 109 patients diagnosed with VAP met the inclusion criteria, and 103 bacterial isolates were cultured from these patients. The most common findings among the 65 VAP episodes were Enterobacteriaceae (28), Pseudomonas aeruginosa (13), Haemophilus influenzae (12) and Staphylococcus aureus (8). Patients with no antibiotic treatment at the onset of VAP had significantly more H. influenzae (p = 0.035) and Gram-positive pathogenic bacteria (p = 0.019). There was no difference in incidence of P. aeruginosa between early-and late-onset VAP. Resistant bacteria were found in 18% of the patients.}}, author = {{Ahl, Jonas and Tham, Johan and Walder, Mats and Melander, Eva and Odenholt, Inga}}, issn = {{1651-1980}}, language = {{eng}}, number = {{6-7}}, pages = {{469--474}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Bacterial aetiology in ventilator-associated pneumonia at a Swedish university hospital}}, url = {{http://dx.doi.org/10.3109/00365541003621494}}, doi = {{10.3109/00365541003621494}}, volume = {{42}}, year = {{2010}}, }