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Viktigt behandla riskfaktorer vid kritisk extremitetsischemi

Gottsäter, Anders LU and Wahlberg, Eric (2007) In Läkartidningen 104(11). p.4-860
Abstract
Patients with chronic critical limb ischaemia (CLI) have a one-year mortality of around 20%, and a ten-year survival of around 25%, mainly due to concomitant cardio- and cerebrovascular atherosclerotic disease. Risk factors for the development of peripheral atherosclerosis and CLI are the same as for cardio- and cerebrovascular atherosclerosis; diabetes mellitus, hyperlipidaemia, arterial hypertension, and smoking are common in CLI patients. As risk factor studies in CLI and peripheral arterial occlusive disease (PAOD) are few, treatment recommendations are often based on studies in patients with cardio- or cerebrovascular atherosclerosis and it can therefore not be definitely established that the recommendations are adequate for CLI... (More)
Patients with chronic critical limb ischaemia (CLI) have a one-year mortality of around 20%, and a ten-year survival of around 25%, mainly due to concomitant cardio- and cerebrovascular atherosclerotic disease. Risk factors for the development of peripheral atherosclerosis and CLI are the same as for cardio- and cerebrovascular atherosclerosis; diabetes mellitus, hyperlipidaemia, arterial hypertension, and smoking are common in CLI patients. As risk factor studies in CLI and peripheral arterial occlusive disease (PAOD) are few, treatment recommendations are often based on studies in patients with cardio- or cerebrovascular atherosclerosis and it can therefore not be definitely established that the recommendations are adequate for CLI patients. While waiting for specific studies, CLI patients should be treated according to current guidelines for other atherosclerotic patients. Medical risk factor treatment in CLI is often suboptimal in relation to recommendations, however, and both better treatment and more studies of medical risk factors in CLI patients are therefore needed. (Less)
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author
organization
alternative title
Treatment of risk factors in critical extremity ischemia is important
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Arterial Occlusive Diseases: complications, Arterial Occlusive Diseases: mortality, Atherosclerosis: complications, Atherosclerosis: drug therapy, Cardiovascular Diseases: complications, Cardiovascular Diseases: drug therapy, Diabetes Complications: drug therapy, Humans, Hyperlipidemias: complications, Hyperlipidemias: drug therapy, Hypertension: complications, Hypertension: drug therapy, Ischemia: complications, Ischemia: drug therapy, Ischemia: mortality, Leg: blood supply, Limb Salvage, Arterial Occlusive Diseases: drug therapy, Practice Guidelines, Prognosis, Risk Factors, Smoking: adverse effects, Smoking Cessation, Survival Rate
in
Läkartidningen
volume
104
issue
11
pages
4 - 860
external identifiers
  • scopus:33947398375
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
fe285c73-b48e-4717-8d16-f8de4d4446bd (old id 167500)
alternative location
http://ltarkiv.lakartidningen.se/artNo33138
date added to LUP
2007-07-20 14:52:16
date last changed
2017-01-01 06:49:15
@article{fe285c73-b48e-4717-8d16-f8de4d4446bd,
  abstract     = {Patients with chronic critical limb ischaemia (CLI) have a one-year mortality of around 20%, and a ten-year survival of around 25%, mainly due to concomitant cardio- and cerebrovascular atherosclerotic disease. Risk factors for the development of peripheral atherosclerosis and CLI are the same as for cardio- and cerebrovascular atherosclerosis; diabetes mellitus, hyperlipidaemia, arterial hypertension, and smoking are common in CLI patients. As risk factor studies in CLI and peripheral arterial occlusive disease (PAOD) are few, treatment recommendations are often based on studies in patients with cardio- or cerebrovascular atherosclerosis and it can therefore not be definitely established that the recommendations are adequate for CLI patients. While waiting for specific studies, CLI patients should be treated according to current guidelines for other atherosclerotic patients. Medical risk factor treatment in CLI is often suboptimal in relation to recommendations, however, and both better treatment and more studies of medical risk factors in CLI patients are therefore needed.},
  author       = {Gottsäter, Anders and Wahlberg, Eric},
  issn         = {0023-7205},
  keyword      = {Arterial Occlusive Diseases: complications,Arterial Occlusive Diseases: mortality,Atherosclerosis: complications,Atherosclerosis: drug therapy,Cardiovascular Diseases: complications,Cardiovascular Diseases: drug therapy,Diabetes Complications: drug therapy,Humans,Hyperlipidemias: complications,Hyperlipidemias: drug therapy,Hypertension: complications,Hypertension: drug therapy,Ischemia: complications,Ischemia: drug therapy,Ischemia: mortality,Leg: blood supply,Limb Salvage,Arterial Occlusive Diseases: drug therapy,Practice Guidelines,Prognosis,Risk Factors,Smoking: adverse effects,Smoking Cessation,Survival Rate},
  language     = {swe},
  number       = {11},
  pages        = {4--860},
  series       = {Läkartidningen},
  title        = {Viktigt behandla riskfaktorer vid kritisk extremitetsischemi},
  volume       = {104},
  year         = {2007},
}