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Atherosclerotic Vascular Events in a Multinational Inception Cohort of Systemic Lupus Erythematosus

Urowitz, M. B.; Gladman, D.; Ibanez, D.; Bae, S. C.; Sanchez-Guerrero, J.; Gordon, C.; Clarke, A.; Bernatsky, S.; Fortin, P. R. and Hanly, J. G., et al. (2010) In Arthritis Care and Research1988-01-01+01:002000-01-01+01:00 62(6). p.881-887
Abstract
Objective. To describe vascular events during an 8-year followup in a multicenter systemic lupus erythematosus (SLE) inception cohort and their attribution to atherosclerosis. Methods. Clinical data, including comorbidities, were recorded yearly. Vascular events were recorded and attributed to atherosclerosis or not. All of the events met standard clinical criteria. Factors associated with atherosclerotic vascular events were analyzed using descriptive statistics, t-tests, and chi-square tests. Stepwise multivariate logistic regression was used to assess the association of factors with vascular events attributed to atherosclerosis. Results. Since 2000, 1,249 patients have been entered into the cohort. There have been 97 vascular events in... (More)
Objective. To describe vascular events during an 8-year followup in a multicenter systemic lupus erythematosus (SLE) inception cohort and their attribution to atherosclerosis. Methods. Clinical data, including comorbidities, were recorded yearly. Vascular events were recorded and attributed to atherosclerosis or not. All of the events met standard clinical criteria. Factors associated with atherosclerotic vascular events were analyzed using descriptive statistics, t-tests, and chi-square tests. Stepwise multivariate logistic regression was used to assess the association of factors with vascular events attributed to atherosclerosis. Results. Since 2000, 1,249 patients have been entered into the cohort. There have been 97 vascular events in 72 patients, including: myocardial infarction (n = 13), angina (n = 15), congestive heart failure (n = 24), peripheral vascular disease (n = 8), transient ischemic attack (n = 13), stroke (n = 23), and pacemaker insertion (n = 1). Fifty of the events were attributed to active lupus, 31 events in 2 (Less)
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organization
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Contribution to journal
publication status
published
subject
in
Arthritis Care and Research1988-01-01+01:002000-01-01+01:00
volume
62
issue
6
pages
881 - 887
publisher
John Wiley & Sons
external identifiers
  • wos:000280979800020
  • scopus:77953084931
ISSN
2151-4658
DOI
10.1002/acr.20122
language
English
LU publication?
yes
id
a1c59e94-e629-4b45-b399-c0f7ec6c214c (old id 1677142)
date added to LUP
2010-09-21 16:04:16
date last changed
2018-07-01 03:00:24
@article{a1c59e94-e629-4b45-b399-c0f7ec6c214c,
  abstract     = {Objective. To describe vascular events during an 8-year followup in a multicenter systemic lupus erythematosus (SLE) inception cohort and their attribution to atherosclerosis. Methods. Clinical data, including comorbidities, were recorded yearly. Vascular events were recorded and attributed to atherosclerosis or not. All of the events met standard clinical criteria. Factors associated with atherosclerotic vascular events were analyzed using descriptive statistics, t-tests, and chi-square tests. Stepwise multivariate logistic regression was used to assess the association of factors with vascular events attributed to atherosclerosis. Results. Since 2000, 1,249 patients have been entered into the cohort. There have been 97 vascular events in 72 patients, including: myocardial infarction (n = 13), angina (n = 15), congestive heart failure (n = 24), peripheral vascular disease (n = 8), transient ischemic attack (n = 13), stroke (n = 23), and pacemaker insertion (n = 1). Fifty of the events were attributed to active lupus, 31 events in 2},
  author       = {Urowitz, M. B. and Gladman, D. and Ibanez, D. and Bae, S. C. and Sanchez-Guerrero, J. and Gordon, C. and Clarke, A. and Bernatsky, S. and Fortin, P. R. and Hanly, J. G. and Wallace, D. J. and Isenberg, D. and Rahman, A. and Alarcon, G. S. and Merrill, J. T. and Ginzler, E. and Khamashta, M. and Nived, Ola and Sturfelt, Gunnar and Bruce, I. N. and Steinsson, K. and Manzi, S. and Ramsey-Goldman, R. and Dooley, M. A. and Zoma, A. and Kalunian, K. and Ramos, M. and Van Vollenhoven, R. F. and Aranow, C. and Stoll, T. and Petri, M. and Maddison, P.},
  issn         = {2151-4658},
  language     = {eng},
  number       = {6},
  pages        = {881--887},
  publisher    = {John Wiley & Sons},
  series       = {Arthritis Care and Research1988-01-01+01:002000-01-01+01:00},
  title        = {Atherosclerotic Vascular Events in a Multinational Inception Cohort of Systemic Lupus Erythematosus},
  url          = {http://dx.doi.org/10.1002/acr.20122},
  volume       = {62},
  year         = {2010},
}