Crossed over repair of the femoral sensory and motor branches influences N-CAM
Saito, Harukazu ; Kanje, Martin LU and Dahlin, Lars LU
(2010)
In NeuroReport
21(12).
p.841-845
- Abstract
- N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both the repairs. After a straight repair N-CAM area increased to the control values in both branches. In contrast, a crossed over repair resulted in a continuous increase of N-CAM in the motor branch, whereas the area in the sensory branch returned slowly to control values. N-CAM is influenced by an intentionally misdirected outgrowth of motor and... (More)
- N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both the repairs. After a straight repair N-CAM area increased to the control values in both branches. In contrast, a crossed over repair resulted in a continuous increase of N-CAM in the motor branch, whereas the area in the sensory branch returned slowly to control values. N-CAM is influenced by an intentionally misdirected outgrowth of motor and sensory axons after nerve repair. NeuroReport 21:841-845 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1677879
- author
- Saito, Harukazu
; Kanje, Martin
LU
and Dahlin, Lars
LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- neurofilaments, nerve repair, nerve regeneration, N-CAM, axons, misdirection, non-myelinating, Schwann cells
- in
- NeuroReport
- volume
- 21
- issue
- 12
- pages
- 841 - 845
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000280592900010
- scopus:77955231671
- pmid:20622691
- ISSN
- 1473-558X
- DOI
- 10.1097/WNR.0b013e32833d40e2
- language
- English
- LU publication?
- yes
- id
- b8d23cd2-08c6-4014-878c-a8af286cf243 (old id 1677879)
- date added to LUP
- 2016-04-01 09:56:04
- date last changed
- 2023-08-30 13:37:39
@article{b8d23cd2-08c6-4014-878c-a8af286cf243,
abstract = {{N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both the repairs. After a straight repair N-CAM area increased to the control values in both branches. In contrast, a crossed over repair resulted in a continuous increase of N-CAM in the motor branch, whereas the area in the sensory branch returned slowly to control values. N-CAM is influenced by an intentionally misdirected outgrowth of motor and sensory axons after nerve repair. NeuroReport 21:841-845 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.}},
author = {{Saito, Harukazu and Kanje, Martin and Dahlin, Lars}},
issn = {{1473-558X}},
keywords = {{neurofilaments; nerve repair; nerve regeneration; N-CAM; axons; misdirection; non-myelinating; Schwann cells}},
language = {{eng}},
number = {{12}},
pages = {{841--845}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{NeuroReport}},
title = {{Crossed over repair of the femoral sensory and motor branches influences N-CAM}},
url = {{http://dx.doi.org/10.1097/WNR.0b013e32833d40e2}},
doi = {{10.1097/WNR.0b013e32833d40e2}},
volume = {{21}},
year = {{2010}},
}