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Evolution of nucleotide sequences and expression patterns of hydrophobin genes in the ectomycorrhizal fungus Paxillus involutus

Rajashekar, Balaji LU ; Samson, Peter LU ; Johansson, Tomas LU and Tunlid, Anders LU (2007) In New Phytologist 174(2). p.399-411
Abstract
Hydrophobins are small, secreted proteins that play important roles in the development of pathogenic and symbiotic fungi. Evolutionary mechanisms generating sequence and expression divergence among members in hydrophobin gene families are largely unknown.

Seven hydrophobin (hyd) genes and one hyd pseudogene were isolated from strains of the ectomycorrhizal fungus Paxillus involutus. Sequences were analysed using phylogenetic methods. Expression profiles were inferred from microarray experiments.



The hyd genes included both young (recently diverged) and old duplicates. Some young hyd genes exhibited an initial phase of enhanced sequence evolution owing to relaxed or positive selection. There was no significant... (More)
Hydrophobins are small, secreted proteins that play important roles in the development of pathogenic and symbiotic fungi. Evolutionary mechanisms generating sequence and expression divergence among members in hydrophobin gene families are largely unknown.

Seven hydrophobin (hyd) genes and one hyd pseudogene were isolated from strains of the ectomycorrhizal fungus Paxillus involutus. Sequences were analysed using phylogenetic methods. Expression profiles were inferred from microarray experiments.



The hyd genes included both young (recently diverged) and old duplicates. Some young hyd genes exhibited an initial phase of enhanced sequence evolution owing to relaxed or positive selection. There was no significant association between sequence divergence and variation in expression levels. However, three hyd genes displayed a shift in the expression levels or an altered tissue specificity following duplication.



The Paxillus hyd genes evolve according to the so-called birth-and-death model in which some duplicates are maintained for a long time, whereas others are inactivated through mutations. The role of subfunctionalization and/or neofunctionalization for preserving the hyd duplicates in the genome is discussed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ectomycorrhiza, expression patterns, gene duplication, neofunctionalization, hydrophobin, subfunctionalization, Paxillus involutus
in
New Phytologist
volume
174
issue
2
pages
399 - 411
publisher
Wiley-Blackwell
external identifiers
  • wos:000245413900022
  • scopus:33947389171
ISSN
1469-8137
DOI
10.1111/j.1469-8137.2007.02022.x
language
English
LU publication?
yes
id
b2309b50-c649-431f-a631-81ce0bd82ee4 (old id 168605)
date added to LUP
2007-06-29 14:29:04
date last changed
2017-10-22 03:50:05
@article{b2309b50-c649-431f-a631-81ce0bd82ee4,
  abstract     = {Hydrophobins are small, secreted proteins that play important roles in the development of pathogenic and symbiotic fungi. Evolutionary mechanisms generating sequence and expression divergence among members in hydrophobin gene families are largely unknown. <br/><br>
Seven hydrophobin (hyd) genes and one hyd pseudogene were isolated from strains of the ectomycorrhizal fungus Paxillus involutus. Sequences were analysed using phylogenetic methods. Expression profiles were inferred from microarray experiments.<br/><br>
<br/><br>
The hyd genes included both young (recently diverged) and old duplicates. Some young hyd genes exhibited an initial phase of enhanced sequence evolution owing to relaxed or positive selection. There was no significant association between sequence divergence and variation in expression levels. However, three hyd genes displayed a shift in the expression levels or an altered tissue specificity following duplication.<br/><br>
<br/><br>
The Paxillus hyd genes evolve according to the so-called birth-and-death model in which some duplicates are maintained for a long time, whereas others are inactivated through mutations. The role of subfunctionalization and/or neofunctionalization for preserving the hyd duplicates in the genome is discussed.},
  author       = {Rajashekar, Balaji and Samson, Peter and Johansson, Tomas and Tunlid, Anders},
  issn         = {1469-8137},
  keyword      = {ectomycorrhiza,expression patterns,gene duplication,neofunctionalization,hydrophobin,subfunctionalization,Paxillus involutus},
  language     = {eng},
  number       = {2},
  pages        = {399--411},
  publisher    = {Wiley-Blackwell},
  series       = {New Phytologist},
  title        = {Evolution of nucleotide sequences and expression patterns of hydrophobin genes in the ectomycorrhizal fungus Paxillus involutus},
  url          = {http://dx.doi.org/10.1111/j.1469-8137.2007.02022.x},
  volume       = {174},
  year         = {2007},
}