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miRNA in mycosis fungoides and skin inflammation.

Persson, Jenny L LU (2013) In APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 121(11). p.1017-1019
Abstract
In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
volume
121
issue
11
pages
1017 - 1019
publisher
Blackwell Munksgaard
external identifiers
  • wos:000326027200001
  • pmid:24106870
  • scopus:84886309176
  • pmid:24106870
ISSN
1600-0463
DOI
10.1111/apm.12186
language
English
LU publication?
yes
id
1686d04e-1869-44cc-8783-5444019cf39b (old id 4143504)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24106870?dopt=Abstract
date added to LUP
2016-04-01 10:56:02
date last changed
2025-10-14 11:55:38
@article{1686d04e-1869-44cc-8783-5444019cf39b,
  abstract     = {{In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.}},
  author       = {{Persson, Jenny L}},
  issn         = {{1600-0463}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{1017--1019}},
  publisher    = {{Blackwell Munksgaard}},
  series       = {{APMIS : acta pathologica, microbiologica, et immunologica Scandinavica}},
  title        = {{miRNA in mycosis fungoides and skin inflammation.}},
  url          = {{http://dx.doi.org/10.1111/apm.12186}},
  doi          = {{10.1111/apm.12186}},
  volume       = {{121}},
  year         = {{2013}},
}