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miRNA in mycosis fungoides and skin inflammation.

Persson, Jenny L LU (2013) In APMIS : acta pathologica, microbiologica, et immunologica Scandinavica1988-01-01+01:00 121(11). p.1017-1019
Abstract
In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica1988-01-01+01:00
volume
121
issue
11
pages
1017 - 1019
publisher
John Wiley & Sons
external identifiers
  • wos:000326027200001
  • pmid:24106870
  • scopus:84886309176
ISSN
1600-0463
DOI
10.1111/apm.12186
language
English
LU publication?
yes
id
1686d04e-1869-44cc-8783-5444019cf39b (old id 4143504)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24106870?dopt=Abstract
date added to LUP
2013-11-02 23:02:05
date last changed
2019-02-20 02:56:28
@article{1686d04e-1869-44cc-8783-5444019cf39b,
  abstract     = {In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.},
  author       = {Persson, Jenny L},
  issn         = {1600-0463},
  language     = {eng},
  number       = {11},
  pages        = {1017--1019},
  publisher    = {John Wiley & Sons},
  series       = { APMIS : acta pathologica, microbiologica, et immunologica Scandinavica1988-01-01+01:00},
  title        = {miRNA in mycosis fungoides and skin inflammation.},
  url          = {http://dx.doi.org/10.1111/apm.12186},
  volume       = {121},
  year         = {2013},
}