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Separation of deformable hydrogel microparticles in deterministic lateral displacement devices

Ghasemi, Masoomeh LU ; Holm, Stefan H. LU ; Beech, Jason P. LU ; Björnmalm, Mattias and Tegenfeldt, Jonas O. LU orcid (2012) 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 p.1672-1674
Abstract

To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deformability and their overall behavior in the device. Future work will expand the approach to a range of particle shapes and to particles with varied hydrogel composition to independently control the mechanical properties of the material.

Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Deformability, Deterministic lateral displacement, Hydrogels, Separation
host publication
Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
pages
3 pages
publisher
Chemical and Biological Microsystems Society
conference name
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
conference location
Okinawa, Japan
conference dates
2012-10-28 - 2012-11-01
external identifiers
  • scopus:84901751262
ISBN
9780979806452
language
English
LU publication?
yes
id
169ae6ab-3225-4cd4-b877-9528521f830b
date added to LUP
2018-10-20 08:50:15
date last changed
2023-09-08 09:26:29
@inproceedings{169ae6ab-3225-4cd4-b877-9528521f830b,
  abstract     = {{<p>To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deformability and their overall behavior in the device. Future work will expand the approach to a range of particle shapes and to particles with varied hydrogel composition to independently control the mechanical properties of the material.</p>}},
  author       = {{Ghasemi, Masoomeh and Holm, Stefan H. and Beech, Jason P. and Björnmalm, Mattias and Tegenfeldt, Jonas O.}},
  booktitle    = {{Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012}},
  isbn         = {{9780979806452}},
  keywords     = {{Deformability; Deterministic lateral displacement; Hydrogels; Separation}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{1672--1674}},
  publisher    = {{Chemical and Biological Microsystems Society}},
  title        = {{Separation of deformable hydrogel microparticles in deterministic lateral displacement devices}},
  year         = {{2012}},
}