Pancreatic function, quality of life and costs at long-term follow-up after acute pancreatitis.
(2010) In World Journal of Gastroenterology 16(39). p.4944-4951- Abstract
- AIM: To evaluate long-term endocrine and exocrine pancreatic function, quality of life and health care costs after mild acute pancreatitis and severe acute pancreatitis (SAP). METHODS: Patients prospectively included in 2001-2005 were followed-up after 42 (36-53) mo. Pancreatic function was evaluated with laboratory tests, the oral glucose tolerance test (OGTT), fecal elastase-1 and a questionnaire. Short Form (SF)-36, was completed. RESULTS: Fourteen patients with a history of SAP and 26 with mild acute pancreatitis were included. Plasma glucose after OGTT was higher after SAP (9.2 mmol/L vs 7.0 mmol/L, P = 0.044). Diabetes mellitus or impaired glucose tolerance in fasting plasma glucose and/or 120 min plasma glucose were more common in... (More)
- AIM: To evaluate long-term endocrine and exocrine pancreatic function, quality of life and health care costs after mild acute pancreatitis and severe acute pancreatitis (SAP). METHODS: Patients prospectively included in 2001-2005 were followed-up after 42 (36-53) mo. Pancreatic function was evaluated with laboratory tests, the oral glucose tolerance test (OGTT), fecal elastase-1 and a questionnaire. Short Form (SF)-36, was completed. RESULTS: Fourteen patients with a history of SAP and 26 with mild acute pancreatitis were included. Plasma glucose after OGTT was higher after SAP (9.2 mmol/L vs 7.0 mmol/L, P = 0.044). Diabetes mellitus or impaired glucose tolerance in fasting plasma glucose and/or 120 min plasma glucose were more common in SAP patients (11/14 vs 11/25, P = 0.037). Sick leave, time until the patients could take up recreational activities and time until they had recovered were all longer after SAP (P < 0.001). No significant differences in SF-36 were seen between the groups, or when comparing with age and gender matched reference groups. Total hospital costs, including primary care, follow-up and treatment of complications, were higher after SAP (median €16 572 vs €5000, P < 0.001). CONCLUSION: Endocrine pancreatic function was affected, especially after severe disease. SAP requires greater resource use with long recovery, but most patients regained a good quality of life. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1711054
- author
- Andersson, Bodil LU ; Pendse, Marie-Louise and Andersson, Roland LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- World Journal of Gastroenterology
- volume
- 16
- issue
- 39
- pages
- 4944 - 4951
- publisher
- WJG Press
- external identifiers
-
- wos:000283396600009
- pmid:20954281
- scopus:78049502344
- ISSN
- 1007-9327
- DOI
- 10.3748/wjg.v16.i39.4944
- language
- English
- LU publication?
- yes
- id
- bd58632a-186a-4b9d-9bd2-ea4b2dc36a64 (old id 1711054)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20954281?dopt=Abstract
- date added to LUP
- 2016-04-04 08:39:22
- date last changed
- 2022-03-15 08:35:01
@article{bd58632a-186a-4b9d-9bd2-ea4b2dc36a64, abstract = {{AIM: To evaluate long-term endocrine and exocrine pancreatic function, quality of life and health care costs after mild acute pancreatitis and severe acute pancreatitis (SAP). METHODS: Patients prospectively included in 2001-2005 were followed-up after 42 (36-53) mo. Pancreatic function was evaluated with laboratory tests, the oral glucose tolerance test (OGTT), fecal elastase-1 and a questionnaire. Short Form (SF)-36, was completed. RESULTS: Fourteen patients with a history of SAP and 26 with mild acute pancreatitis were included. Plasma glucose after OGTT was higher after SAP (9.2 mmol/L vs 7.0 mmol/L, P = 0.044). Diabetes mellitus or impaired glucose tolerance in fasting plasma glucose and/or 120 min plasma glucose were more common in SAP patients (11/14 vs 11/25, P = 0.037). Sick leave, time until the patients could take up recreational activities and time until they had recovered were all longer after SAP (P < 0.001). No significant differences in SF-36 were seen between the groups, or when comparing with age and gender matched reference groups. Total hospital costs, including primary care, follow-up and treatment of complications, were higher after SAP (median €16 572 vs €5000, P < 0.001). CONCLUSION: Endocrine pancreatic function was affected, especially after severe disease. SAP requires greater resource use with long recovery, but most patients regained a good quality of life.}}, author = {{Andersson, Bodil and Pendse, Marie-Louise and Andersson, Roland}}, issn = {{1007-9327}}, language = {{eng}}, number = {{39}}, pages = {{4944--4951}}, publisher = {{WJG Press}}, series = {{World Journal of Gastroenterology}}, title = {{Pancreatic function, quality of life and costs at long-term follow-up after acute pancreatitis.}}, url = {{http://dx.doi.org/10.3748/wjg.v16.i39.4944}}, doi = {{10.3748/wjg.v16.i39.4944}}, volume = {{16}}, year = {{2010}}, }