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Particle Size Distribution and Human Respiratory Deposition of Trace Metals in Indoor Work Environments

Akselsson, Roland LU ; Desaedeleer, Georges G.; Johansson, Thomas B LU and Winchester, John W. (1976) In Annals of Occupational Hygiene 19(3-4). p.225-238
Abstract
Respiratory response to inhalation of fine particles has been investigated for the aerosol generated by welding. Particles were sampled using a pair of 5-stage cascade impactors operating at 1 l./min flow rate. The subject exhaled into one impactor through an air ballast arrangement, and the other impactor simultaneously sampled the surrounding air. Particle size fractions were analyzed for principal elemental constituents from sulphur to lead using proton induced X-ray emission, PIXE. The results indicated a complex respiratory response, including both increase in particle size due to exposure to high humidity in the respiratory tract and deposition of particles during inhalation. The response was found to be different for the element... (More)
Respiratory response to inhalation of fine particles has been investigated for the aerosol generated by welding. Particles were sampled using a pair of 5-stage cascade impactors operating at 1 l./min flow rate. The subject exhaled into one impactor through an air ballast arrangement, and the other impactor simultaneously sampled the surrounding air. Particle size fractions were analyzed for principal elemental constituents from sulphur to lead using proton induced X-ray emission, PIXE. The results indicated a complex respiratory response, including both increase in particle size due to exposure to high humidity in the respiratory tract and deposition of particles during inhalation. The response was found to be different for the element group Mn, Cr, Fe, Ni compared to the group K, Ca, Ti by observing the associations among the elements as a function of particle size in the inhaled and exhaled aerosol. However, for respiratory deposition efficiency alone in all runs averaged together, no systematic differences between the different elements are demonstrated at the 99 % confidence level. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
lung deposition, welding aerosols, particle size distribution, elemental composition
in
Annals of Occupational Hygiene
volume
19
issue
3-4
pages
225 - 238
publisher
Oxford University Press
external identifiers
  • scopus:0017056401
ISSN
1475-3162
DOI
10.1093/annhyg/19.3-4.225
language
English
LU publication?
yes
id
4522ad3a-9fab-46e7-a0f7-b99ca7282088 (old id 1764986)
date added to LUP
2011-02-04 13:42:16
date last changed
2017-07-30 03:42:08
@article{4522ad3a-9fab-46e7-a0f7-b99ca7282088,
  abstract     = {Respiratory response to inhalation of fine particles has been investigated for the aerosol generated by welding. Particles were sampled using a pair of 5-stage cascade impactors operating at 1 l./min flow rate. The subject exhaled into one impactor through an air ballast arrangement, and the other impactor simultaneously sampled the surrounding air. Particle size fractions were analyzed for principal elemental constituents from sulphur to lead using proton induced X-ray emission, PIXE. The results indicated a complex respiratory response, including both increase in particle size due to exposure to high humidity in the respiratory tract and deposition of particles during inhalation. The response was found to be different for the element group Mn, Cr, Fe, Ni compared to the group K, Ca, Ti by observing the associations among the elements as a function of particle size in the inhaled and exhaled aerosol. However, for respiratory deposition efficiency alone in all runs averaged together, no systematic differences between the different elements are demonstrated at the 99 % confidence level.},
  author       = {Akselsson, Roland and Desaedeleer, Georges G. and Johansson, Thomas B and Winchester, John W.},
  issn         = {1475-3162},
  keyword      = {lung deposition,welding aerosols,particle size distribution,elemental composition},
  language     = {eng},
  number       = {3-4},
  pages        = {225--238},
  publisher    = {Oxford University Press},
  series       = {Annals of Occupational Hygiene},
  title        = {Particle Size Distribution and Human Respiratory Deposition of Trace Metals in Indoor Work Environments},
  url          = {http://dx.doi.org/10.1093/annhyg/19.3-4.225},
  volume       = {19},
  year         = {1976},
}