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Antiproliferative activity of extracts of some Bolivian medicinal plants

Rodrigo, Gloria LU ; Almanza, Giovanna R.; Åkesson, Björn LU and Duan, Rui-Dong LU (2010) In Journal of Medicinal Plants Research 4(21). p.2204-2210
Abstract
Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity... (More)
Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
colon cancer, cell proliferation, Bolivian plants
in
Journal of Medicinal Plants Research
volume
4
issue
21
pages
2204 - 2210
publisher
Academic Journals
external identifiers
  • wos:000285689600006
  • scopus:78650584427
ISSN
1996-0875
language
English
LU publication?
yes
id
8794b6bb-567c-4da0-aea3-d40e8b09c57b (old id 1811446)
alternative location
http://www.academicjournals.org/JMPR/abstracts/abstracts/abstracts2010/4Nov/Rodrigo%20et%20al.htm
date added to LUP
2011-03-02 13:45:47
date last changed
2018-05-29 10:04:01
@article{8794b6bb-567c-4da0-aea3-d40e8b09c57b,
  abstract     = {Twenty-six plant species from the native flora used in Bolivian folk medicine were selected for studies of bioactivity. They belonged to the following families namely: Asteraceae (11), Brassicaceae (1), Cactaceae (1), Caesalpinaceae (2), Chenopodiaceae (1), Frankeniaceae (1), Geraniaceae (1), Laureaceae (1), Oxalidaceae (1), Piperaceae (1), Plantaginaceae (1), Rosaceae (1), Solanaceae (1) and Verbenaceae (2). Their effects on the proliferation of colon cancer cells (Caco-2) were studied using the WST-1 reagent. The results indicated that four out of 26 ethanolic extracts had a significant antiproliferative activity in this assay from (Schkuhria pinnata, Piper longestylosum, Parastrephia lepidophylla and Erodium cicutarium). The bioactivity of the extracts was correlated with the phytochemical characterization. Further studies of the mechanism of action of the bioactive extracts are needed.},
  author       = {Rodrigo, Gloria and Almanza, Giovanna R. and Åkesson, Björn and Duan, Rui-Dong},
  issn         = {1996-0875},
  keyword      = {colon cancer,cell proliferation,Bolivian plants},
  language     = {eng},
  number       = {21},
  pages        = {2204--2210},
  publisher    = {Academic Journals},
  series       = {Journal of Medicinal Plants Research},
  title        = {Antiproliferative activity of extracts of some Bolivian medicinal plants},
  volume       = {4},
  year         = {2010},
}