Advanced

Diagnosis and Treatment of Common Forms of Tremor

Puschmann, Andreas LU and Wszolek, Zbigniew K. (2011) In Seminars in Neurology 31(1). p.65-77
Abstract
Tremor is the most common movement disorder presenting to an outpatient neurology practice and is defined as a rhythmical, involuntary oscillatory movement of a body part. The authors review the clinical examination, classification, and diagnosis of tremor. The pathophysiology of the more common forms of tremor is outlined, and treatment options are discussed. Essential tremor is characterized primarily by postural and action tremors, may be a neurodegenerative disorder with pathologic changes in the cerebellum, and can be treated with a wide range of pharmacologic and nonpharmacologic methods. Tremor at rest is typical for Parkinson's disease, but may arise independently of a dopaminergic deficit. Enhanced physiologic tremor, intention... (More)
Tremor is the most common movement disorder presenting to an outpatient neurology practice and is defined as a rhythmical, involuntary oscillatory movement of a body part. The authors review the clinical examination, classification, and diagnosis of tremor. The pathophysiology of the more common forms of tremor is outlined, and treatment options are discussed. Essential tremor is characterized primarily by postural and action tremors, may be a neurodegenerative disorder with pathologic changes in the cerebellum, and can be treated with a wide range of pharmacologic and nonpharmacologic methods. Tremor at rest is typical for Parkinson's disease, but may arise independently of a dopaminergic deficit. Enhanced physiologic tremor, intention tremor, and dystonic tremor are discussed. Further differential diagnoses described in this review include drug- or toxin-induced tremor, neuropathic tremor, psychogenic tremor, orthostatic tremor, palatal tremor, tremor in Wilson's disease, and tremor secondary to cerebral lesions, such as Holmes' tremor ( midbrain tremor). An individualized approach to treatment of tremor patients is important, taking into account the degree of disability, including social embarrassment, which the tremor causes in the patient's life. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Tremor, essential tremor, Parkinson's disease, dystonia, pathophysiology
in
Seminars in Neurology
volume
31
issue
1
pages
65 - 77
publisher
Georg Thieme Verlag
external identifiers
  • wos:000287358800008
  • scopus:79951803767
ISSN
0271-8235
DOI
10.1055/s-0031-1271312
language
English
LU publication?
yes
id
6f2d8720-d8b8-482d-8e66-7db2363a1566 (old id 1876889)
date added to LUP
2011-04-01 10:58:46
date last changed
2017-11-12 03:38:05
@article{6f2d8720-d8b8-482d-8e66-7db2363a1566,
  abstract     = {Tremor is the most common movement disorder presenting to an outpatient neurology practice and is defined as a rhythmical, involuntary oscillatory movement of a body part. The authors review the clinical examination, classification, and diagnosis of tremor. The pathophysiology of the more common forms of tremor is outlined, and treatment options are discussed. Essential tremor is characterized primarily by postural and action tremors, may be a neurodegenerative disorder with pathologic changes in the cerebellum, and can be treated with a wide range of pharmacologic and nonpharmacologic methods. Tremor at rest is typical for Parkinson's disease, but may arise independently of a dopaminergic deficit. Enhanced physiologic tremor, intention tremor, and dystonic tremor are discussed. Further differential diagnoses described in this review include drug- or toxin-induced tremor, neuropathic tremor, psychogenic tremor, orthostatic tremor, palatal tremor, tremor in Wilson's disease, and tremor secondary to cerebral lesions, such as Holmes' tremor ( midbrain tremor). An individualized approach to treatment of tremor patients is important, taking into account the degree of disability, including social embarrassment, which the tremor causes in the patient's life.},
  author       = {Puschmann, Andreas and Wszolek, Zbigniew K.},
  issn         = {0271-8235},
  keyword      = {Tremor,essential tremor,Parkinson's disease,dystonia,pathophysiology},
  language     = {eng},
  number       = {1},
  pages        = {65--77},
  publisher    = {Georg Thieme Verlag},
  series       = {Seminars in Neurology},
  title        = {Diagnosis and Treatment of Common Forms of Tremor},
  url          = {http://dx.doi.org/10.1055/s-0031-1271312},
  volume       = {31},
  year         = {2011},
}