How to detect a dwarf - in vivo imaging of nanoparticles in the lung.
(2011) In Nanomedicine: Nanotechnology, Biology and Medicine 7(6). p.753-762- Abstract
- Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy.... (More)
- Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy. Studies based on these techniques may contribute to the development of novel NP-based drug delivery systems and contrast agents. In addition, they may provide completely new insights into nanotoxicological processes. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1883717
- author
- Roller, Jonas ; Laschke, Matthias LU ; Tschernig, Thomas ; Schramm, René ; Veith, Nils T ; Thorlacius, Henrik LU and Menger, Michael D
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Imaging, Nanoparticles, Lung, Computed tomography, Intravital, fluorescence microscopy
- in
- Nanomedicine: Nanotechnology, Biology and Medicine
- volume
- 7
- issue
- 6
- pages
- 753 - 762
- publisher
- Elsevier
- external identifiers
-
- wos:000297699900011
- pmid:21419874
- scopus:82255193873
- pmid:21419874
- ISSN
- 1549-9642
- DOI
- 10.1016/j.nano.2011.02.010
- language
- English
- LU publication?
- yes
- id
- 09765255-46ec-4b29-b1b4-f5bd854f6b59 (old id 1883717)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21419874?dopt=Abstract
- date added to LUP
- 2016-04-01 10:08:19
- date last changed
- 2022-01-25 20:08:32
@article{09765255-46ec-4b29-b1b4-f5bd854f6b59, abstract = {{Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy. Studies based on these techniques may contribute to the development of novel NP-based drug delivery systems and contrast agents. In addition, they may provide completely new insights into nanotoxicological processes.}}, author = {{Roller, Jonas and Laschke, Matthias and Tschernig, Thomas and Schramm, René and Veith, Nils T and Thorlacius, Henrik and Menger, Michael D}}, issn = {{1549-9642}}, keywords = {{Imaging; Nanoparticles; Lung; Computed tomography; Intravital; fluorescence microscopy}}, language = {{eng}}, number = {{6}}, pages = {{753--762}}, publisher = {{Elsevier}}, series = {{Nanomedicine: Nanotechnology, Biology and Medicine}}, title = {{How to detect a dwarf - in vivo imaging of nanoparticles in the lung.}}, url = {{http://dx.doi.org/10.1016/j.nano.2011.02.010}}, doi = {{10.1016/j.nano.2011.02.010}}, volume = {{7}}, year = {{2011}}, }