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How to detect a dwarf - in vivo imaging of nanoparticles in the lung.

Roller, Jonas; Laschke, Matthias LU ; Tschernig, Thomas; Schramm, René; Veith, Nils T; Thorlacius, Henrik LU and Menger, Michael D (2011) In Nanomedicine: Nanotechnology, Biology and Medicine 7(6). p.753-762
Abstract
Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy.... (More)
Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy. Studies based on these techniques may contribute to the development of novel NP-based drug delivery systems and contrast agents. In addition, they may provide completely new insights into nanotoxicological processes. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Imaging, Nanoparticles, Lung, Computed tomography, Intravital, fluorescence microscopy
in
Nanomedicine: Nanotechnology, Biology and Medicine
volume
7
issue
6
pages
753 - 762
publisher
Elsevier
external identifiers
  • wos:000297699900011
  • pmid:21419874
  • scopus:82255193873
ISSN
1549-9642
DOI
10.1016/j.nano.2011.02.010
language
English
LU publication?
yes
id
09765255-46ec-4b29-b1b4-f5bd854f6b59 (old id 1883717)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21419874?dopt=Abstract
date added to LUP
2011-04-01 17:11:18
date last changed
2017-11-19 03:05:36
@article{09765255-46ec-4b29-b1b4-f5bd854f6b59,
  abstract     = {Nanotechnology is a rapidly developing field in science and industry. The exposure to nanoparticles (NPs) will steadily grow in the future and, thus, there is an urgent need to study potential impacts of the interaction between NPs and the human body. The respiratory tract is the route of entry for all accidentally inhaled NPs. Moreover, NPs may intentionally be delivered into the lung as contrast agents and drug delivery systems. The present review provides an overview of currently used techniques for the in vivo imaging of NPs in the lung, including X-ray, computed tomography (CT), gamma camera imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), near-infrared imaging and intravital fluorescence microscopy. Studies based on these techniques may contribute to the development of novel NP-based drug delivery systems and contrast agents. In addition, they may provide completely new insights into nanotoxicological processes.},
  author       = {Roller, Jonas and Laschke, Matthias and Tschernig, Thomas and Schramm, René and Veith, Nils T and Thorlacius, Henrik and Menger, Michael D},
  issn         = {1549-9642},
  keyword      = {Imaging,Nanoparticles,Lung,Computed tomography,Intravital,fluorescence microscopy},
  language     = {eng},
  number       = {6},
  pages        = {753--762},
  publisher    = {Elsevier},
  series       = {Nanomedicine: Nanotechnology, Biology and Medicine},
  title        = {How to detect a dwarf - in vivo imaging of nanoparticles in the lung.},
  url          = {http://dx.doi.org/10.1016/j.nano.2011.02.010},
  volume       = {7},
  year         = {2011},
}