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When von Willebrand disease comes into age - A matter of change?

Miesbach, Wolfgang and Berntorp, Erik LU (2011) In European Journal of Haematology 86. p.496-501
Abstract
The population of elderly patients with von Willebrand Disease (VWD) is growing due to the improvement of medical care. The increase of co-morbidities and their treatment as well as standard preventive measures like anti-platelet or anticoagulation therapy constitute a challenge in the overall treatment of patients with coagulation disorders. Due to the lack of literature on older VWD patients, we discuss different aspects related to ageing in those patients. Plasma levels of von Willebrand factor (VWF) and factor VIII (FVIII), bleeding symptoms, treatment requirements and co-morbidities are possibly changing with age. Development of an evidence-based approach to the management of ageing VWD patients is therefore necessary.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Haematology
volume
86
pages
496 - 501
publisher
Wiley-Blackwell
external identifiers
  • wos:000290731000006
  • pmid:21418329
  • scopus:79955999740
ISSN
1600-0609
DOI
10.1111/j.1600-0609.2011.01611.x
language
English
LU publication?
yes
id
18ef0977-cf31-4164-819e-b96e348fe616 (old id 1883757)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21418329?dopt=Abstract
date added to LUP
2011-04-01 17:01:15
date last changed
2017-01-22 04:14:30
@article{18ef0977-cf31-4164-819e-b96e348fe616,
  abstract     = {The population of elderly patients with von Willebrand Disease (VWD) is growing due to the improvement of medical care. The increase of co-morbidities and their treatment as well as standard preventive measures like anti-platelet or anticoagulation therapy constitute a challenge in the overall treatment of patients with coagulation disorders. Due to the lack of literature on older VWD patients, we discuss different aspects related to ageing in those patients. Plasma levels of von Willebrand factor (VWF) and factor VIII (FVIII), bleeding symptoms, treatment requirements and co-morbidities are possibly changing with age. Development of an evidence-based approach to the management of ageing VWD patients is therefore necessary.},
  author       = {Miesbach, Wolfgang and Berntorp, Erik},
  issn         = {1600-0609},
  language     = {eng},
  pages        = {496--501},
  publisher    = {Wiley-Blackwell},
  series       = {European Journal of Haematology},
  title        = {When von Willebrand disease comes into age - A matter of change?},
  url          = {http://dx.doi.org/10.1111/j.1600-0609.2011.01611.x},
  volume       = {86},
  year         = {2011},
}