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Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update)

Rayman, Gerry ; Vas, Prashanth ; Dhatariya, Ketan ; Driver, Vickie ; Hartemann, Agnes ; Londahl, Magnus LU ; Piaggesi, Alberto ; Apelqvist, Jan LU ; Attinger, Chris and Game, Fran (2020) In Diabetes/Metabolism Research and Reviews 36(S1).
Abstract

The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of the literature centred on the following: the Population (P), Intervention (I), Comparator (C) and Outcomes (O) framework; the use of the SIGN guideline/Cochrane review system; and the 21 point scoring system advocated by IWGDF/EWMA. This has resulted in 13 recommendations. The recommendation on sharp debridement and the selection of dressings remain unchanged from the last recommendations published in 2016. The... (More)

The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of the literature centred on the following: the Population (P), Intervention (I), Comparator (C) and Outcomes (O) framework; the use of the SIGN guideline/Cochrane review system; and the 21 point scoring system advocated by IWGDF/EWMA. This has resulted in 13 recommendations. The recommendation on sharp debridement and the selection of dressings remain unchanged from the last recommendations published in 2016. The recommendation to consider negative pressure wound therapy in post-surgical wounds and the judicious use of hyperbaric oxygen therapy in certain non-healing ischaemic ulcers also remains unchanged. Recommendations against the use of growth factors, autologous platelet gels, bioengineered skin products, ozone, topical carbon dioxide, nitric oxide or interventions reporting improvement of ulcer healing through an alteration of the physical environment or through other systemic medical or nutritional means also remain. New recommendations include consideration of the use of sucrose-octasulfate impregnated dressings in difficult to heal neuro-ischaemic ulcers and consideration of the use of autologous combined leucocyte, platelet and fibrin patch in ulcers that are difficult to heal, in both cases when used in addition to best standard of care. A further new recommendation is the consideration of topical placental derived products when used in addition to best standard of care.

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author
; ; ; ; ; ; ; ; and
author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diabetic foot, dressing, foot ulcer, guidelines, wound healing
in
Diabetes/Metabolism Research and Reviews
volume
36
issue
S1
article number
e3283
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85081726715
  • pmid:32176450
ISSN
1520-7552
DOI
10.1002/dmrr.3283
language
English
LU publication?
yes
id
1b6b87b4-ea61-487b-913c-409dffd6c89b
date added to LUP
2020-12-16 14:35:46
date last changed
2024-06-14 05:09:35
@article{1b6b87b4-ea61-487b-913c-409dffd6c89b,
  abstract     = {{<p>The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of the literature centred on the following: the Population (P), Intervention (I), Comparator (C) and Outcomes (O) framework; the use of the SIGN guideline/Cochrane review system; and the 21 point scoring system advocated by IWGDF/EWMA. This has resulted in 13 recommendations. The recommendation on sharp debridement and the selection of dressings remain unchanged from the last recommendations published in 2016. The recommendation to consider negative pressure wound therapy in post-surgical wounds and the judicious use of hyperbaric oxygen therapy in certain non-healing ischaemic ulcers also remains unchanged. Recommendations against the use of growth factors, autologous platelet gels, bioengineered skin products, ozone, topical carbon dioxide, nitric oxide or interventions reporting improvement of ulcer healing through an alteration of the physical environment or through other systemic medical or nutritional means also remain. New recommendations include consideration of the use of sucrose-octasulfate impregnated dressings in difficult to heal neuro-ischaemic ulcers and consideration of the use of autologous combined leucocyte, platelet and fibrin patch in ulcers that are difficult to heal, in both cases when used in addition to best standard of care. A further new recommendation is the consideration of topical placental derived products when used in addition to best standard of care.</p>}},
  author       = {{Rayman, Gerry and Vas, Prashanth and Dhatariya, Ketan and Driver, Vickie and Hartemann, Agnes and Londahl, Magnus and Piaggesi, Alberto and Apelqvist, Jan and Attinger, Chris and Game, Fran}},
  issn         = {{1520-7552}},
  keywords     = {{diabetic foot; dressing; foot ulcer; guidelines; wound healing}},
  language     = {{eng}},
  number       = {{S1}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Diabetes/Metabolism Research and Reviews}},
  title        = {{Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update)}},
  url          = {{http://dx.doi.org/10.1002/dmrr.3283}},
  doi          = {{10.1002/dmrr.3283}},
  volume       = {{36}},
  year         = {{2020}},
}