Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation
(2022) In npj Materials Degradation 6(1).- Abstract
Magnesium (Mg) alloys are becoming increasingly important in the biomedical field as temporary bone implants. However, the biodegradation process of Mg alloys is highly complex and recent findings suggest that oxygen (O2) consumption is non-negligible. In this study, we give experimental proof of O2 consumption during Mg degradation under physiological conditions. Specifically, we study pure Mg, Mg–6 wt%Ag and Mg–5 wt%Gd in Hanks’ balanced salt solution and Dulbecco’s modified Eagle’s medium. We show that O2 consumption and hydrogen evolution are inversely correlated and that O2 concentrations remain below 7.5% in certain cases, which could have significant implications for bone healing.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1e7c9748-07b5-425a-bbdc-e1aac9e841ab
- author
- Zeller-Plumhoff, Berit LU ; Akkineni, Ashwini Rahul ; Helmholz, Heike ; Orlov, Dmytro LU ; Mosshammer, Maria ; Kühl, Michael ; Willumeit-Römer, Regine and Gelinsky, Michael
- organization
- publishing date
- 2022-12
- type
- Contribution to journal
- publication status
- published
- subject
- in
- npj Materials Degradation
- volume
- 6
- issue
- 1
- article number
- 95
- publisher
- Nature Publishing Group
- external identifiers
-
- scopus:85142162325
- ISSN
- 2397-2106
- DOI
- 10.1038/s41529-022-00302-9
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2022, The Author(s).
- id
- 1e7c9748-07b5-425a-bbdc-e1aac9e841ab
- date added to LUP
- 2022-12-11 21:19:21
- date last changed
- 2023-10-06 13:52:56
@article{1e7c9748-07b5-425a-bbdc-e1aac9e841ab, abstract = {{<p>Magnesium (Mg) alloys are becoming increasingly important in the biomedical field as temporary bone implants. However, the biodegradation process of Mg alloys is highly complex and recent findings suggest that oxygen (O<sub>2</sub>) consumption is non-negligible. In this study, we give experimental proof of O<sub>2</sub> consumption during Mg degradation under physiological conditions. Specifically, we study pure Mg, Mg–6 wt%Ag and Mg–5 wt%Gd in Hanks’ balanced salt solution and Dulbecco’s modified Eagle’s medium. We show that O<sub>2</sub> consumption and hydrogen evolution are inversely correlated and that O<sub>2</sub> concentrations remain below 7.5% in certain cases, which could have significant implications for bone healing.</p>}}, author = {{Zeller-Plumhoff, Berit and Akkineni, Ashwini Rahul and Helmholz, Heike and Orlov, Dmytro and Mosshammer, Maria and Kühl, Michael and Willumeit-Römer, Regine and Gelinsky, Michael}}, issn = {{2397-2106}}, language = {{eng}}, number = {{1}}, publisher = {{Nature Publishing Group}}, series = {{npj Materials Degradation}}, title = {{Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation}}, url = {{http://dx.doi.org/10.1038/s41529-022-00302-9}}, doi = {{10.1038/s41529-022-00302-9}}, volume = {{6}}, year = {{2022}}, }