Whole-heart four-dimensional flow can be acquired with preserved quality without respiratory gating, facilitating clinical use : A head-to-head comparison

Kanski, Mikael; Töger, Johannes; Steding-Ehrenborg, Katarina; Xanthis, Christos; Bloch, Karin Markenroth; Heiberg, Einar; Carlsson, Marcus; Arheden, Håkan

Whole-heart four-dimensional flow can be acquired with preserved quality without respiratory gating, facilitating clinical use : A head-to-head comparison

Mark

Kanski, Mikael ^LU ; Töger, Johannes ^LU ; Steding-Ehrenborg, Katarina ^LU ; Xanthis, Christos ^LU ; Bloch, Karin Markenroth ^LU

; Heiberg, Einar ^LU ; Carlsson, Marcus ^LU and Arheden, Håkan ^LU (2015) In BMC Medical Imaging 15(1).

Abstract: Background: Respiratory gating is often used in 4D-flow acquisition to reduce motion artifacts. However, gating increases scan time. The aim of this study was to investigate if respiratory gating can be excluded from 4D flow acquisitions without affecting quantitative intracardiac parameters. Methods: Eight volunteers underwent CMR at 1.5 T with a 5-channel coil (5ch). Imaging included 2D flow measurements and whole-heart 4D flow with and without respiratory gating (Resp(+), Resp(-)). Stroke volume (SV), particle-trace volumes, kinetic energy, and vortex-ring volume were obtained from 4D flow-data. These parameters were compared between 5ch Resp(+) and 5ch Resp(-). In addition, 20 patients with heart failure were scanned using a... (More); Background: Respiratory gating is often used in 4D-flow acquisition to reduce motion artifacts. However, gating increases scan time. The aim of this study was to investigate if respiratory gating can be excluded from 4D flow acquisitions without affecting quantitative intracardiac parameters. Methods: Eight volunteers underwent CMR at 1.5 T with a 5-channel coil (5ch). Imaging included 2D flow measurements and whole-heart 4D flow with and without respiratory gating (Resp(+), Resp(-)). Stroke volume (SV), particle-trace volumes, kinetic energy, and vortex-ring volume were obtained from 4D flow-data. These parameters were compared between 5ch Resp(+) and 5ch Resp(-). In addition, 20 patients with heart failure were scanned using a 32-channel coil (32ch), and particle-trace volumes were compared to planimetric SV. Paired comparisons were performed using Wilcoxon's test and correlation analysis using Pearson r. Agreement was assessed as bias ± SD. Results: Stroke volume from 4D flow was lower compared to 2D flow both with and without respiratory gating (5ch Resp(+) 88 ± 18 vs 97 ± 24.0, p = 0.001; 5ch Resp(-) 86 ± 16 vs 97.1 ± 22.7, p < 0.01). There was a good correlation between Resp(+) and Resp(-) for particle-trace derived volumes (R² = 0.82, 0.2 ± 9.4 ml), mean kinetic energy (R² = 0.86, 0.07 ± 0.21 mJ), peak kinetic energy (R² = 0.88, 0.14 ± 0.77 mJ), and vortex-ring volume (R² = 0.70, -2.5 ± 9.4 ml). Furthermore, good correlation was found between particle-trace volume and planimetric SV in patients for 32ch Resp(-) (R² = 0.62, -4.2 ± 17.6 ml) and in healthy volunteers for 5ch Resp(+) (R² = 0.89, -11 ± 7 ml), and 5ch Resp(-) (R² = 0.93, -7.5 ± 5.4 ml), Average scan duration for Resp(-) was shorter compared to Resp(+) (27 ± 9 min vs 61 ± 19 min, p < 0.05). Conclusions: Whole-heart 4D flow can be acquired with preserved quantitative results without respiratory gating, facilitating clinical use.
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Please use this url to cite or link to this publication: https://lup.lub.lu.se/record/7485472

author

Kanski, Mikael ^LU ; Töger, Johannes ^LU ; Steding-Ehrenborg, Katarina ^LU ; Xanthis, Christos ^LU ; Bloch, Karin Markenroth ^LU

; Heiberg, Einar ^LU ; Carlsson, Marcus ^LU and Arheden, Håkan ^LU

organization

publishing date

2015-06-18

type

Contribution to journal

publication status

published

subject

Cardiac and Cardiovascular Systems

keywords

4D flow, Cardiac MRI, Kinetic energy, Particle trace, Respiratory gating, Vortex ring size

in

BMC Medical Imaging

volume

15

issue

1

article number

20

publisher

BioMed Central (BMC)

external identifiers

pmid:26080805
wos:000356410200001
pmid:26080805
scopus:84931094170

ISSN

1471-2342

DOI

10.1186/s12880-015-0061-4

language

English

LU publication?

yes

id

1e8f448d-ddc9-4dac-b99d-ae091487ebbd (old id 7485472)

alternative location

http://www.ncbi.nlm.nih.gov/pubmed/26080805?dopt=Abstract

date added to LUP

2016-04-01 13:54:22

date last changed

2022-03-21 21:10:12

@article{1e8f448d-ddc9-4dac-b99d-ae091487ebbd,
  abstract     = {{<p>Background: Respiratory gating is often used in 4D-flow acquisition to reduce motion artifacts. However, gating increases scan time. The aim of this study was to investigate if respiratory gating can be excluded from 4D flow acquisitions without affecting quantitative intracardiac parameters. Methods: Eight volunteers underwent CMR at 1.5 T with a 5-channel coil (5ch). Imaging included 2D flow measurements and whole-heart 4D flow with and without respiratory gating (Resp(+), Resp(-)). Stroke volume (SV), particle-trace volumes, kinetic energy, and vortex-ring volume were obtained from 4D flow-data. These parameters were compared between 5ch Resp(+) and 5ch Resp(-). In addition, 20 patients with heart failure were scanned using a 32-channel coil (32ch), and particle-trace volumes were compared to planimetric SV. Paired comparisons were performed using Wilcoxon's test and correlation analysis using Pearson r. Agreement was assessed as bias ± SD. Results: Stroke volume from 4D flow was lower compared to 2D flow both with and without respiratory gating (5ch Resp(+) 88 ± 18 vs 97 ± 24.0, p = 0.001; 5ch Resp(-) 86 ± 16 vs 97.1 ± 22.7, p &lt; 0.01). There was a good correlation between Resp(+) and Resp(-) for particle-trace derived volumes (R<sup>2</sup> = 0.82, 0.2 ± 9.4 ml), mean kinetic energy (R<sup>2</sup> = 0.86, 0.07 ± 0.21 mJ), peak kinetic energy (R<sup>2</sup> = 0.88, 0.14 ± 0.77 mJ), and vortex-ring volume (R<sup>2</sup> = 0.70, -2.5 ± 9.4 ml). Furthermore, good correlation was found between particle-trace volume and planimetric SV in patients for 32ch Resp(-) (R<sup>2</sup> = 0.62, -4.2 ± 17.6 ml) and in healthy volunteers for 5ch Resp(+) (R<sup>2</sup> = 0.89, -11 ± 7 ml), and 5ch Resp(-) (R<sup>2</sup> = 0.93, -7.5 ± 5.4 ml), Average scan duration for Resp(-) was shorter compared to Resp(+) (27 ± 9 min vs 61 ± 19 min, p &lt; 0.05). Conclusions: Whole-heart 4D flow can be acquired with preserved quantitative results without respiratory gating, facilitating clinical use.</p>}},
  author       = {{Kanski, Mikael and Töger, Johannes and Steding-Ehrenborg, Katarina and Xanthis, Christos and Bloch, Karin Markenroth and Heiberg, Einar and Carlsson, Marcus and Arheden, Håkan}},
  issn         = {{1471-2342}},
  keywords     = {{4D flow; Cardiac MRI; Kinetic energy; Particle trace; Respiratory gating; Vortex ring size}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Medical Imaging}},
  title        = {{Whole-heart four-dimensional flow can be acquired with preserved quality without respiratory gating, facilitating clinical use : A head-to-head comparison}},
  url          = {{https://lup.lub.lu.se/search/files/3659563/8610816}},
  doi          = {{10.1186/s12880-015-0061-4}},
  volume       = {{15}},
  year         = {{2015}},
}

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Whole-heart four-dimensional flow can be acquired with preserved quality without respiratory gating, facilitating clinical use : A head-to-head comparison