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Experience with percutaneous titanium implants in the head and neck: a clinical and histological study

Holgers, Kajsa-Mia ; Bjursten, Lars Magnus LU ; Thomsen, Peter ; Ericson, Lars E and Tjellström, Anders (1989) In Journal of Investigative Surgery 2(1). p.7-16
Abstract
Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells.... (More)
Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells. This suggests a response directed against exogenous agents rather than an allergic reaction against the implant per se. (Less)
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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
implants, titanium, percutaneous, clinical, histology, histochemistry
in
Journal of Investigative Surgery
volume
2
issue
1
pages
7 - 16
publisher
Taylor & Francis
external identifiers
  • pmid:2487400
  • scopus:0024949626
ISSN
0894-1939
DOI
10.3109/08941938909016500
language
English
LU publication?
no
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Bioimplant Research (013242910)
id
1ed36be1-9bfb-4d51-8ce7-a2d9dc7ff92a (old id 1104494)
date added to LUP
2016-04-01 12:06:34
date last changed
2021-05-09 05:03:16
@article{1ed36be1-9bfb-4d51-8ce7-a2d9dc7ff92a,
  abstract     = {{Percutaneous implants have been associated with numerous problems. However, by using skin-penetrating, bone-anchored titanium implants, developed by Professor Branemark at the Department of Anatomy, University of Goteborg, good long-term results have been observed. These implants have been in clinical use for anchorage of bone-conducting hearing aids and facial prostheses since 1977 and 1979, respectively. The total number of implants is approximately 700. Less than 4% of the observations have shown significant irritation. Biopsies from 33 patients were collected for histological studies. In the irritated skin there was an increased number of inflammatory cells, mainly polymorphonuclear cells, B-cells, and plasma cells but not T-cells. This suggests a response directed against exogenous agents rather than an allergic reaction against the implant per se.}},
  author       = {{Holgers, Kajsa-Mia and Bjursten, Lars Magnus and Thomsen, Peter and Ericson, Lars E and Tjellström, Anders}},
  issn         = {{0894-1939}},
  keywords     = {{implants; titanium; percutaneous; clinical; histology; histochemistry}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{7--16}},
  publisher    = {{Taylor & Francis}},
  series       = {{Journal of Investigative Surgery}},
  title        = {{Experience with percutaneous titanium implants in the head and neck: a clinical and histological study}},
  url          = {{http://dx.doi.org/10.3109/08941938909016500}},
  doi          = {{10.3109/08941938909016500}},
  volume       = {{2}},
  year         = {{1989}},
}