Duration of methicillin-resistant Staphylococcus aureus colonization after diagnosis: A four-year experience from southern Sweden
(2011) In Scandinavian Journal of Infectious Diseases 43(6-7). p.456-462- Abstract
- Background: The duration of colonization with methicillin-resistant Staphylococcus aureus (MRSA) is not well known and there is debate as to whether a patient colonized with MRSA ever can be defined as 'MRSA-negative'. Methods: Since 2003 all notified MRSA cases have been systematically followed in Skane County, southern Sweden. Cultures are taken from the nares, throat, perineum and possible skin lesions. Contact tracing is conducted. The screening program continues as long as cultures are positive and then until 1 y of consecutive negative cultures for MRSA is completed. Results: Of the 578 MRSA cases during 2003-2006, 535 were included in this retrospective study. The median duration of colonization with MRSA was 5.9 months. Having... (More)
- Background: The duration of colonization with methicillin-resistant Staphylococcus aureus (MRSA) is not well known and there is debate as to whether a patient colonized with MRSA ever can be defined as 'MRSA-negative'. Methods: Since 2003 all notified MRSA cases have been systematically followed in Skane County, southern Sweden. Cultures are taken from the nares, throat, perineum and possible skin lesions. Contact tracing is conducted. The screening program continues as long as cultures are positive and then until 1 y of consecutive negative cultures for MRSA is completed. Results: Of the 578 MRSA cases during 2003-2006, 535 were included in this retrospective study. The median duration of colonization with MRSA was 5.9 months. Having household contacts with MRSA, young age, spa-type t002 and colonization in 2 or more locations, were significantly associated with a longer duration of colonization. Having a clinical infection treated with antibiotics (compared to clinical infection with no antibiotic treatment or asymptomatic carriage) was significantly associated with a shorter carriage time. Eradication treatment was associated with a shorter carriage time. Conclusion: These results may have implications for the management of patients with MRSA carriage. The study indicates that MRSA carriage can be defined as 'negative' in a follow-up program and shows the importance of performing contact tracing among household members. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2049432
- author
- Larsson, Anna-Karin A LU ; Gustafsson, Eva LU ; Nilsson, Anna LU ; Odenholt, Inga LU ; Ringberg, Håkan LU and Melander, Eva LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Antibiotic resistance, MRSA, community associated, risk factor, contact, tracing
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 43
- issue
- 6-7
- pages
- 456 - 462
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000291662600007
- scopus:79959240699
- pmid:21366406
- ISSN
- 1651-1980
- DOI
- 10.3109/00365548.2011.562530
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Clinical Microbiology, Malmö (013011000), Division of Infection Medicine (SUS) (013008000), Department of Clinical Sciences, Lund (013230000), Infectious Diseases Research Unit (013242010)
- id
- 9b2d23fc-3beb-4e93-b970-b6373fe66714 (old id 2049432)
- date added to LUP
- 2016-04-01 13:48:57
- date last changed
- 2022-01-27 21:16:04
@article{9b2d23fc-3beb-4e93-b970-b6373fe66714, abstract = {{Background: The duration of colonization with methicillin-resistant Staphylococcus aureus (MRSA) is not well known and there is debate as to whether a patient colonized with MRSA ever can be defined as 'MRSA-negative'. Methods: Since 2003 all notified MRSA cases have been systematically followed in Skane County, southern Sweden. Cultures are taken from the nares, throat, perineum and possible skin lesions. Contact tracing is conducted. The screening program continues as long as cultures are positive and then until 1 y of consecutive negative cultures for MRSA is completed. Results: Of the 578 MRSA cases during 2003-2006, 535 were included in this retrospective study. The median duration of colonization with MRSA was 5.9 months. Having household contacts with MRSA, young age, spa-type t002 and colonization in 2 or more locations, were significantly associated with a longer duration of colonization. Having a clinical infection treated with antibiotics (compared to clinical infection with no antibiotic treatment or asymptomatic carriage) was significantly associated with a shorter carriage time. Eradication treatment was associated with a shorter carriage time. Conclusion: These results may have implications for the management of patients with MRSA carriage. The study indicates that MRSA carriage can be defined as 'negative' in a follow-up program and shows the importance of performing contact tracing among household members.}}, author = {{Larsson, Anna-Karin A and Gustafsson, Eva and Nilsson, Anna and Odenholt, Inga and Ringberg, Håkan and Melander, Eva}}, issn = {{1651-1980}}, keywords = {{Antibiotic resistance; MRSA; community associated; risk factor; contact; tracing}}, language = {{eng}}, number = {{6-7}}, pages = {{456--462}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Duration of methicillin-resistant Staphylococcus aureus colonization after diagnosis: A four-year experience from southern Sweden}}, url = {{https://lup.lub.lu.se/search/files/3608605/2255858.pdf}}, doi = {{10.3109/00365548.2011.562530}}, volume = {{43}}, year = {{2011}}, }