Third-trimester conditional reference values for longitudinal fetal growth assessment
Basuki, Tri Rahmat ; Triunfo, Stefania ; Caradeux, Javier ; Eixarch, Elisenda ; Hansson, Stefan LU
; Gratacos, Eduard
and Figueras, Francesc
(2018)
In Fetal Diagnosis and Therapy
43(1).
p.34-39
- Abstract
Objectives: The aim of this study was to derive longitudinal reference values of fetal growth (estimated fetal weight [EFW] and abdominal circumference [AC]) during the third trimester and to develop coefficients for conditional growth assessment. Patients and Methods: A prospective cohort study was conducted involving consecutive singleton pregnancies in a low-risk population for a routine third-trimester scan at 30+0-34+6 weeks and follow-up at 37+0-38+6 weeks for an additional ultrasound. Statistical analysis was based on multilevel modeling using MLwiN software. Unconditional centiles were calculated from z-values at each gestational age, and conditional centiles were calculated from... (More)
Objectives: The aim of this study was to derive longitudinal reference values of fetal growth (estimated fetal weight [EFW] and abdominal circumference [AC]) during the third trimester and to develop coefficients for conditional growth assessment. Patients and Methods: A prospective cohort study was conducted involving consecutive singleton pregnancies in a low-risk population for a routine third-trimester scan at 30+0-34+6 weeks and follow-up at 37+0-38+6 weeks for an additional ultrasound. Statistical analysis was based on multilevel modeling using MLwiN software. Unconditional centiles were calculated from z-values at each gestational age, and conditional centiles were calculated from z-values at a given measurement (30-34 weeks) and the expected measurement (37-38 weeks). Results: At 30-34 weeks, 8 and 9.3% of the fetuses had an unconditional EFW below the 10th and above the 90th centile, respectively. At 37-38 weeks, these figures were 10.3 and 9.3%, respectively. Regarding the unconditional AC, at the first scan, 8.9 and 9.6% had values below the 10th and above the 90th centile, while at the second scan 10.5 and 10.5% had values below the 10th and above the 90th centile, respectively. The proportion with a conditional EFW below the 10th and above the 90th centile was 10.2 and 9.4% at the second scan, respectively. For conditional AC, these figures were 10.7 and 10.3%, respectively. Conclusion: We have produced reference centiles for EFW and AC growth during the third trimester as a useful tool for quantifying growth.
(Less)
- author
- Basuki, Tri Rahmat
; Triunfo, Stefania
; Caradeux, Javier
; Eixarch, Elisenda
; Hansson, Stefan
LU
; Gratacos, Eduard
and Figueras, Francesc
- organization
- publishing date
- 2018-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Abdominal circumference, Conditional reference values, Estimated fetal weight, Gestational age, Longitudinal study, Multilevel modeling
- in
- Fetal Diagnosis and Therapy
- volume
- 43
- issue
- 1
- pages
- 6 pages
- publisher
- Karger
- external identifiers
-
- pmid:28601881
- pmid:28601881
- scopus:85040566845
- ISSN
- 1015-3837
- DOI
- 10.1159/000453261
- language
- English
- LU publication?
- yes
- id
- 205b42f5-81a1-44a7-9753-fe8b68ec601f
- date added to LUP
- 2018-02-05 11:23:09
- date last changed
- 2025-01-08 04:41:21
@article{205b42f5-81a1-44a7-9753-fe8b68ec601f,
abstract = {{<p>Objectives: The aim of this study was to derive longitudinal reference values of fetal growth (estimated fetal weight [EFW] and abdominal circumference [AC]) during the third trimester and to develop coefficients for conditional growth assessment. Patients and Methods: A prospective cohort study was conducted involving consecutive singleton pregnancies in a low-risk population for a routine third-trimester scan at 30<sup>+0</sup>-34<sup>+6</sup> weeks and follow-up at 37<sup>+0</sup>-38<sup>+6</sup> weeks for an additional ultrasound. Statistical analysis was based on multilevel modeling using MLwiN software. Unconditional centiles were calculated from z-values at each gestational age, and conditional centiles were calculated from z-values at a given measurement (30-34 weeks) and the expected measurement (37-38 weeks). Results: At 30-34 weeks, 8 and 9.3% of the fetuses had an unconditional EFW below the 10th and above the 90th centile, respectively. At 37-38 weeks, these figures were 10.3 and 9.3%, respectively. Regarding the unconditional AC, at the first scan, 8.9 and 9.6% had values below the 10th and above the 90th centile, while at the second scan 10.5 and 10.5% had values below the 10th and above the 90th centile, respectively. The proportion with a conditional EFW below the 10th and above the 90th centile was 10.2 and 9.4% at the second scan, respectively. For conditional AC, these figures were 10.7 and 10.3%, respectively. Conclusion: We have produced reference centiles for EFW and AC growth during the third trimester as a useful tool for quantifying growth.</p>}},
author = {{Basuki, Tri Rahmat and Triunfo, Stefania and Caradeux, Javier and Eixarch, Elisenda and Hansson, Stefan and Gratacos, Eduard and Figueras, Francesc}},
issn = {{1015-3837}},
keywords = {{Abdominal circumference; Conditional reference values; Estimated fetal weight; Gestational age; Longitudinal study; Multilevel modeling}},
language = {{eng}},
month = {{01}},
number = {{1}},
pages = {{34--39}},
publisher = {{Karger}},
series = {{Fetal Diagnosis and Therapy}},
title = {{Third-trimester conditional reference values for longitudinal fetal growth assessment}},
url = {{http://dx.doi.org/10.1159/000453261}},
doi = {{10.1159/000453261}},
volume = {{43}},
year = {{2018}},
}