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Influence of a 3-Year Exercise Intervention Program on Fracture Risk, Bone Mass, and Bone Size in Prepubertal Children

Löfgren, Bjarne LU ; Detter, Fredrik LU ; Dencker, Magnus LU ; Stenevi Lundgren, Susanna LU ; Nilsson, Jan-Åke LU and Karlsson, Magnus LU (2011) In Journal of Bone and Mineral Research 26(8). p.1740-1747
Abstract
Published prospective pediatric exercise intervention studies are short term and use skeletal traits as surrogate endpoints for fractures, whereas other reports infer exercise to be associated with more trauma and fractures. This prospective, controlled exercise intervention study therefore followed both skeletal traits and fracture risk for 36 months. Fractures were registered in children aged 7 to 9 years; there were 446 boys and 362 girls in the intervention group (2129 person-years) and 807 boys and 780 girls in the control group (4430 person-years). The intervention included school physical education of 40 minutes per day for 3 years. The control children achieved the Swedish standard of 60 minutes per week. In a subsample of 76 boys... (More)
Published prospective pediatric exercise intervention studies are short term and use skeletal traits as surrogate endpoints for fractures, whereas other reports infer exercise to be associated with more trauma and fractures. This prospective, controlled exercise intervention study therefore followed both skeletal traits and fracture risk for 36 months. Fractures were registered in children aged 7 to 9 years; there were 446 boys and 362 girls in the intervention group (2129 person-years) and 807 boys and 780 girls in the control group (4430 person-years). The intervention included school physical education of 40 minutes per day for 3 years. The control children achieved the Swedish standard of 60 minutes per week. In a subsample of 76 boys and 48 girls in the intervention group and 55 boys and 44 girls in the control group, bone mineral content (BMC, g) and bone width (cm) were followed in the lumbar spine and hip by dual-energy X-ray absorptiometry (DXA). The rate ratio (RR) for fractures was 1.08 (0.71, 1.62) [ mean (95% confidence interval)]. In the DXA-measured children, there were no group differences at baseline in age, anthropometrics, or bone traits. The mean annual gain in the intervention group in lumbar spine BMC was 0.9 SD higher in girls and 0.8 SD higher in boys (both p<.001) and in third lumbar vertebra width 0.4 SD higher in girls and 0.3 SD higher in boys (both p<.05) than in control children. It is concluded that a moderately intense 3-year exercise program in 7- to 9-year-old children increases bone mass and possibly also bone size without increasing fracture risk. (C) 2011 American Society for Bone and Mineral Research. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
BMC, BONE SIZE, CHILDREN, EXERCISE, FRACTURE
in
Journal of Bone and Mineral Research
volume
26
issue
8
pages
1740 - 1747
publisher
AMBMR
external identifiers
  • wos:000293382600007
  • pmid:21381112
  • scopus:79960646180
ISSN
1523-4681
DOI
10.1002/jbmr.381
language
English
LU publication?
yes
id
7887523d-b05d-449f-99f7-8bb24da51130 (old id 2065444)
date added to LUP
2011-09-02 08:27:53
date last changed
2017-10-22 03:29:41
@article{7887523d-b05d-449f-99f7-8bb24da51130,
  abstract     = {Published prospective pediatric exercise intervention studies are short term and use skeletal traits as surrogate endpoints for fractures, whereas other reports infer exercise to be associated with more trauma and fractures. This prospective, controlled exercise intervention study therefore followed both skeletal traits and fracture risk for 36 months. Fractures were registered in children aged 7 to 9 years; there were 446 boys and 362 girls in the intervention group (2129 person-years) and 807 boys and 780 girls in the control group (4430 person-years). The intervention included school physical education of 40 minutes per day for 3 years. The control children achieved the Swedish standard of 60 minutes per week. In a subsample of 76 boys and 48 girls in the intervention group and 55 boys and 44 girls in the control group, bone mineral content (BMC, g) and bone width (cm) were followed in the lumbar spine and hip by dual-energy X-ray absorptiometry (DXA). The rate ratio (RR) for fractures was 1.08 (0.71, 1.62) [ mean (95% confidence interval)]. In the DXA-measured children, there were no group differences at baseline in age, anthropometrics, or bone traits. The mean annual gain in the intervention group in lumbar spine BMC was 0.9 SD higher in girls and 0.8 SD higher in boys (both p&lt;.001) and in third lumbar vertebra width 0.4 SD higher in girls and 0.3 SD higher in boys (both p&lt;.05) than in control children. It is concluded that a moderately intense 3-year exercise program in 7- to 9-year-old children increases bone mass and possibly also bone size without increasing fracture risk. (C) 2011 American Society for Bone and Mineral Research.},
  author       = {Löfgren, Bjarne and Detter, Fredrik and Dencker, Magnus and Stenevi Lundgren, Susanna and Nilsson, Jan-Åke and Karlsson, Magnus},
  issn         = {1523-4681},
  keyword      = {BMC,BONE SIZE,CHILDREN,EXERCISE,FRACTURE},
  language     = {eng},
  number       = {8},
  pages        = {1740--1747},
  publisher    = {AMBMR},
  series       = {Journal of Bone and Mineral Research},
  title        = {Influence of a 3-Year Exercise Intervention Program on Fracture Risk, Bone Mass, and Bone Size in Prepubertal Children},
  url          = {http://dx.doi.org/10.1002/jbmr.381},
  volume       = {26},
  year         = {2011},
}