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Unconventional Zwitterionic State of L-Cysteine

Ataman, Evren LU ; Isvoranu, Cristina LU ; Andersen, Jesper N LU ; Schnadt, Joachim LU and Schulte, Karina LU (2011) In The Journal of Physical Chemistry Letters 2(14). p.1677-1681
Abstract
We report the signature of an unconventional zwitterion in thick (>40 angstrom) L-cysteine films grown at low temperature (100 K) by means of sublimation in ultrahigh vacuum. Using X-ray photoelectron spectroscopy (XPS) we find that protonated amino groups (57%) are less prevalent than in films grown at higher temperatures. A large majority of the protonated amino groups receive the hydrogen through deprotonation of the thiol group (45%) and, in contrast, only a small fraction of the carboxylic groups (13%) is deprotonated. This shows, for the first time, the unconventional zwitterion to be the dominant species in L-cysteine. We believe the unusual growth parameters are responsible for this novel observation.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Journal of Physical Chemistry Letters
volume
2
issue
14
pages
1677 - 1681
publisher
The American Chemical Society
external identifiers
  • wos:000293191800007
  • scopus:79960708588
ISSN
1948-7185
DOI
10.1021/jz2006918
language
English
LU publication?
yes
id
dd48be2a-c788-4622-a5cd-db8e9120d63d (old id 2072098)
date added to LUP
2011-08-26 09:57:19
date last changed
2017-09-10 03:54:23
@article{dd48be2a-c788-4622-a5cd-db8e9120d63d,
  abstract     = {We report the signature of an unconventional zwitterion in thick (>40 angstrom) L-cysteine films grown at low temperature (100 K) by means of sublimation in ultrahigh vacuum. Using X-ray photoelectron spectroscopy (XPS) we find that protonated amino groups (57%) are less prevalent than in films grown at higher temperatures. A large majority of the protonated amino groups receive the hydrogen through deprotonation of the thiol group (45%) and, in contrast, only a small fraction of the carboxylic groups (13%) is deprotonated. This shows, for the first time, the unconventional zwitterion to be the dominant species in L-cysteine. We believe the unusual growth parameters are responsible for this novel observation.},
  author       = {Ataman, Evren and Isvoranu, Cristina and Andersen, Jesper N and Schnadt, Joachim and Schulte, Karina},
  issn         = {1948-7185},
  language     = {eng},
  number       = {14},
  pages        = {1677--1681},
  publisher    = {The American Chemical Society},
  series       = {The Journal of Physical Chemistry Letters},
  title        = {Unconventional Zwitterionic State of L-Cysteine},
  url          = {http://dx.doi.org/10.1021/jz2006918},
  volume       = {2},
  year         = {2011},
}