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Novel supermacroporous dextran gels

Plieva, Fatima LU ; Oknianska, Alina LU ; Degerman, Eva LU ; Galaev, Igor LU and Mattiasson, Bo LU (2006) In Journal of Biomaterials Science. Polymer Edition 17(10). p.1075-1092
Abstract
Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering... (More)
Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering and cell culture. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cell, interconnected pores, swelling, dextran, supermacroporous gel, scaffolds
in
Journal of Biomaterials Science. Polymer Edition
volume
17
issue
10
pages
1075 - 1092
publisher
VSP BV
external identifiers
  • wos:000242631900001
  • scopus:33750098499
ISSN
0920-5063
DOI
10.1163/156856206778530722
language
English
LU publication?
yes
id
20bf4905-d895-4e2f-9e0d-a57a24b913fc (old id 683678)
date added to LUP
2007-12-20 13:49:47
date last changed
2019-03-17 04:17:46
@article{20bf4905-d895-4e2f-9e0d-a57a24b913fc,
  abstract     = {Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering and cell culture.},
  author       = {Plieva, Fatima and Oknianska, Alina and Degerman, Eva and Galaev, Igor and Mattiasson, Bo},
  issn         = {0920-5063},
  keyword      = {cell,interconnected pores,swelling,dextran,supermacroporous gel,scaffolds},
  language     = {eng},
  number       = {10},
  pages        = {1075--1092},
  publisher    = {VSP BV},
  series       = {Journal of Biomaterials Science. Polymer Edition},
  title        = {Novel supermacroporous dextran gels},
  url          = {http://dx.doi.org/10.1163/156856206778530722},
  volume       = {17},
  year         = {2006},
}