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Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern Sweden

Rosenquist, K; Wennerberg, Johan LU ; Schildt, Elsy-Britt LU ; Bladström, Anna LU ; Hansson, Bengt-Göran LU and Andersson, G (2005) In Acta Oto-Laryngologica 125(12). p.1327-1336
Abstract
Conclusion. Our results show that average and poor oral hygiene and inadequate dental status are independent risk factors for oral and oropharyngeal squamous cell carcinoma ( OOSCC), irrespective of tobacco and alcohol consumption. Objective. To evaluate a possible relationship between oral cancer, oral hygiene, dental status, oral mucosal lesions and some lifestyle factors in a population- based case- control study. Material and methods. Between September 2000 and January 2004, 132/ 165 ( 80%) of all incident cases of OOSCC and 320/ 396 ( 81%) of the intended eligible matched controls participated in the study. Cases and controls were subjected to an identical oral examination. A standardized protocol specially designed for the study was... (More)
Conclusion. Our results show that average and poor oral hygiene and inadequate dental status are independent risk factors for oral and oropharyngeal squamous cell carcinoma ( OOSCC), irrespective of tobacco and alcohol consumption. Objective. To evaluate a possible relationship between oral cancer, oral hygiene, dental status, oral mucosal lesions and some lifestyle factors in a population- based case- control study. Material and methods. Between September 2000 and January 2004, 132/ 165 ( 80%) of all incident cases of OOSCC and 320/ 396 ( 81%) of the intended eligible matched controls participated in the study. Cases and controls were subjected to an identical oral examination. A standardized protocol specially designed for the study was used. Results. After adjusting for tobacco and alcohol consumption, average oral hygiene ( OR 2.0; 95% CI 1.1 - 3.6) and poor oral hygiene ( OR 5.3; 95% CI 2.5 - 11.3) emerged as significant risk factors for OOSCC. More than 20 lost teeth ( OR 3.4; 95% CI 1.4 - 8.5), > 5 defective teeth ( OR 3.1; 95% CI 1.2 - 8.2) and poorly fitting or defective complete dentures ( OR 3.8; 95% CI 1.3 - 11.4) were significant risk factors. Regular dental check- ups were associated with a decreased risk of OOSCC ( OR 0.4; 95% CI 0.2 - 0.6). (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
oral cancer, lesions, mucosal, human papillomavirus, epidemiology, dental status, education, oral hygiene
in
Acta Oto-Laryngologica
volume
125
issue
12
pages
1327 - 1336
publisher
Taylor & Francis
external identifiers
  • pmid:16303683
  • wos:000233473600014
  • scopus:28444469433
ISSN
1651-2251
DOI
10.1080/00016480510012273
language
English
LU publication?
yes
id
0ef0e5e9-6bd0-41a6-aed1-dabd099ca18a (old id 212411)
date added to LUP
2007-08-21 09:15:47
date last changed
2017-11-12 04:01:09
@article{0ef0e5e9-6bd0-41a6-aed1-dabd099ca18a,
  abstract     = {Conclusion. Our results show that average and poor oral hygiene and inadequate dental status are independent risk factors for oral and oropharyngeal squamous cell carcinoma ( OOSCC), irrespective of tobacco and alcohol consumption. Objective. To evaluate a possible relationship between oral cancer, oral hygiene, dental status, oral mucosal lesions and some lifestyle factors in a population- based case- control study. Material and methods. Between September 2000 and January 2004, 132/ 165 ( 80%) of all incident cases of OOSCC and 320/ 396 ( 81%) of the intended eligible matched controls participated in the study. Cases and controls were subjected to an identical oral examination. A standardized protocol specially designed for the study was used. Results. After adjusting for tobacco and alcohol consumption, average oral hygiene ( OR 2.0; 95% CI 1.1 - 3.6) and poor oral hygiene ( OR 5.3; 95% CI 2.5 - 11.3) emerged as significant risk factors for OOSCC. More than 20 lost teeth ( OR 3.4; 95% CI 1.4 - 8.5), > 5 defective teeth ( OR 3.1; 95% CI 1.2 - 8.2) and poorly fitting or defective complete dentures ( OR 3.8; 95% CI 1.3 - 11.4) were significant risk factors. Regular dental check- ups were associated with a decreased risk of OOSCC ( OR 0.4; 95% CI 0.2 - 0.6).},
  author       = {Rosenquist, K and Wennerberg, Johan and Schildt, Elsy-Britt and Bladström, Anna and Hansson, Bengt-Göran and Andersson, G},
  issn         = {1651-2251},
  keyword      = {oral cancer,lesions,mucosal,human papillomavirus,epidemiology,dental status,education,oral hygiene},
  language     = {eng},
  number       = {12},
  pages        = {1327--1336},
  publisher    = {Taylor & Francis},
  series       = {Acta Oto-Laryngologica},
  title        = {Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern Sweden},
  url          = {http://dx.doi.org/10.1080/00016480510012273},
  volume       = {125},
  year         = {2005},
}