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IMRT treatment planning - A comparative inter-system and intor-centre planning exercise of the ESTRO QUASIMODO group

Bohsung, J; Gillis, S; Arrans, R; Bakai, A; De Wagter, C; Knöös, Tommy LU ; Mijnheer, BJ; Paiusco, M; Perrin, BA and Welleweerd, H, et al. (2005) In Radiotherapy and Oncology 76(3). p.354-361
Abstract
Background and purpose: The purpose of this work was a comparison of realistic IMRT plans based on the same CT-image data set and a common predefined set of dose objectives for the planning target volume and the organs at risk. This work was part of the larger European QUASIMODO IMRT verification project. Materials and methods: Eleven IMRT. plans were produced by nine different European groups, each applying a representative set of. clinically used IMRT treatment planning systems. The plans produced were to be deliverable in a clinically acceptable treatment time with the local technical equipment. All plans were characterized using a set of different quality measures such as dose-volume histograms, number of monitor units and treatment... (More)
Background and purpose: The purpose of this work was a comparison of realistic IMRT plans based on the same CT-image data set and a common predefined set of dose objectives for the planning target volume and the organs at risk. This work was part of the larger European QUASIMODO IMRT verification project. Materials and methods: Eleven IMRT. plans were produced by nine different European groups, each applying a representative set of. clinically used IMRT treatment planning systems. The plans produced were to be deliverable in a clinically acceptable treatment time with the local technical equipment. All plans were characterized using a set of different quality measures such as dose-volume histograms, number of monitor units and treatment time. Results: Only one plan was able to fulfil all dose objectives strictly; six plans failed some of the objectives but were still considered to be clinically acceptable; four plans were not able to reach the objectives. Additional quality scores such as the number of monitor units and treatment time showed large variations, which mainly depend on the delivery technique. Conclusion: The presented planning study showed that with nearly all presently available IMRT planning and delivery systems comparable dose distributions could be achieved if the planning goals are clearly defined in advance. (Less)
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Contribution to journal
publication status
published
subject
keywords
intensity-modulated radiation therapy, treatment planning, multi-centre, intercomparison
in
Radiotherapy and Oncology
volume
76
issue
3
pages
354 - 361
publisher
Elsevier
external identifiers
  • pmid:16154218
  • wos:000232900800017
  • scopus:22444432140
ISSN
1879-0887
DOI
10.1016/j.radonc.2005.08.003
language
English
LU publication?
yes
id
9d752ec0-89d6-431b-817d-636b77b1aade (old id 214430)
date added to LUP
2007-08-15 09:08:45
date last changed
2017-10-22 03:48:07
@article{9d752ec0-89d6-431b-817d-636b77b1aade,
  abstract     = {Background and purpose: The purpose of this work was a comparison of realistic IMRT plans based on the same CT-image data set and a common predefined set of dose objectives for the planning target volume and the organs at risk. This work was part of the larger European QUASIMODO IMRT verification project. Materials and methods: Eleven IMRT. plans were produced by nine different European groups, each applying a representative set of. clinically used IMRT treatment planning systems. The plans produced were to be deliverable in a clinically acceptable treatment time with the local technical equipment. All plans were characterized using a set of different quality measures such as dose-volume histograms, number of monitor units and treatment time. Results: Only one plan was able to fulfil all dose objectives strictly; six plans failed some of the objectives but were still considered to be clinically acceptable; four plans were not able to reach the objectives. Additional quality scores such as the number of monitor units and treatment time showed large variations, which mainly depend on the delivery technique. Conclusion: The presented planning study showed that with nearly all presently available IMRT planning and delivery systems comparable dose distributions could be achieved if the planning goals are clearly defined in advance.},
  author       = {Bohsung, J and Gillis, S and Arrans, R and Bakai, A and De Wagter, C and Knöös, Tommy and Mijnheer, BJ and Paiusco, M and Perrin, BA and Welleweerd, H and Williams, P},
  issn         = {1879-0887},
  keyword      = {intensity-modulated radiation therapy,treatment planning,multi-centre,intercomparison},
  language     = {eng},
  number       = {3},
  pages        = {354--361},
  publisher    = {Elsevier},
  series       = {Radiotherapy and Oncology},
  title        = {IMRT treatment planning - A comparative inter-system and intor-centre planning exercise of the ESTRO QUASIMODO group},
  url          = {http://dx.doi.org/10.1016/j.radonc.2005.08.003},
  volume       = {76},
  year         = {2005},
}