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Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.

Dykes, Josefina LU ; Lenshof, Andreas LU ; Åstrand-Grundström, Ingbritt LU ; Laurell, Thomas LU and Scheding, Stefan LU (2011) In PLoS ONE 6(8).
Abstract
Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
6
issue
8
article number
e23074
publisher
Public Library of Science
external identifiers
  • wos:000293774300020
  • pmid:21857996
  • scopus:79961216177
  • pmid:21857996
ISSN
1932-6203
DOI
10.1371/journal.pone.0023074
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Hematology and Transfusion Medicine (013041100), Stem Cell Center (013022011), Biomedical Engineering (011200011), Hematopoietic Stem Cell Laboratory (013022012), Hematology/Transplantation (013022014)
id
f8a2f731-6830-4b16-bdbb-59bf64fc355e (old id 2150804)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21857996?dopt=Abstract
date added to LUP
2016-04-04 09:23:49
date last changed
2021-09-29 01:39:03
@article{f8a2f731-6830-4b16-bdbb-59bf64fc355e,
  abstract     = {Excessive collection of platelets is an unwanted side effect in current centrifugation-based peripheral blood progenitor cell (PBPC) apheresis. We investigated a novel microchip-based acoustophoresis technique, utilizing ultrasonic standing wave forces for the removal of platelets from PBPC products. By applying an acoustic standing wave field onto a continuously flowing cell suspension in a micro channel, cells can be separated from the surrounding media depending on their physical properties.},
  author       = {Dykes, Josefina and Lenshof, Andreas and Åstrand-Grundström, Ingbritt and Laurell, Thomas and Scheding, Stefan},
  issn         = {1932-6203},
  language     = {eng},
  number       = {8},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.},
  url          = {https://lup.lub.lu.se/search/files/5313226/2256507.pdf},
  doi          = {10.1371/journal.pone.0023074},
  volume       = {6},
  year         = {2011},
}