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Psychotropic drugs and accidents in Scania, Sweden.

Modén, Birgit LU ; Ohlsson, Henrik LU ; Merlo, Juan LU and Rosvall, Maria LU (2011) In European Journal of Public Health
Abstract
BACKGROUND: Injuries are second to cardiovascular diseases, the main cause of hospital care in Sweden. The aim of the present study was to investigate the associations between medication with psychotropic drugs and injuries from two types of accidents, i.e. falling accidents and transportation accidents, respectively, in the whole population aged ≥18 years in the county of Scania, Sweden. METHODS: Injuries from falling accidents and transportation accidents during 2007 were identified from the Region Healthcare database. Exposure to psychotropic medication expressed as defined daily doses (DDDs) during the 18 months before baseline, i.e. 1 January 2007, was identified from the Swedish Medication Register. The results were stratified by sex... (More)
BACKGROUND: Injuries are second to cardiovascular diseases, the main cause of hospital care in Sweden. The aim of the present study was to investigate the associations between medication with psychotropic drugs and injuries from two types of accidents, i.e. falling accidents and transportation accidents, respectively, in the whole population aged ≥18 years in the county of Scania, Sweden. METHODS: Injuries from falling accidents and transportation accidents during 2007 were identified from the Region Healthcare database. Exposure to psychotropic medication expressed as defined daily doses (DDDs) during the 18 months before baseline, i.e. 1 January 2007, was identified from the Swedish Medication Register. The results were stratified by sex and three age groups, i.e. 18-34 years, 35-64 years and ≥65. The logistic regression models were adjusted for marital status, country of origin, income, previous disease and previous accidents. RESULTS: Using psychotropic drugs was associated with increased odds for a falling accident in all age groups, however, with a dose-response relationship only among the elderly. Furthermore, using psychotropic drugs was associated with increased odds of transportation accidents in the ages 18-34 years and 35-64 years, respectively, but with a weaker association among the elderly. A similar pattern of association was seen for specific groups of psychotropic drugs: opioids, anti-depressants and anxiolytics/hypnotics/sedatives. CONCLUSIONS: In this total population-based study, there were nearly consistent associations between use of psychotropic drugs and injuries from falling accidents and transportation accidents, even after adjustment for previous accidents, previous disease and socio-demographic variables. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Public Health
publisher
Oxford University Press
external identifiers
  • wos:000309465400029
  • pmid:21896615
  • scopus:84866983290
ISSN
1101-1262
DOI
10.1093/eurpub/ckr110
language
English
LU publication?
yes
id
60fdc637-aaf4-4f50-a65b-5bfd9284c55c (old id 2169098)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21896615?dopt=Abstract
date added to LUP
2011-10-03 09:38:50
date last changed
2017-01-01 07:29:28
@article{60fdc637-aaf4-4f50-a65b-5bfd9284c55c,
  abstract     = {BACKGROUND: Injuries are second to cardiovascular diseases, the main cause of hospital care in Sweden. The aim of the present study was to investigate the associations between medication with psychotropic drugs and injuries from two types of accidents, i.e. falling accidents and transportation accidents, respectively, in the whole population aged ≥18 years in the county of Scania, Sweden. METHODS: Injuries from falling accidents and transportation accidents during 2007 were identified from the Region Healthcare database. Exposure to psychotropic medication expressed as defined daily doses (DDDs) during the 18 months before baseline, i.e. 1 January 2007, was identified from the Swedish Medication Register. The results were stratified by sex and three age groups, i.e. 18-34 years, 35-64 years and ≥65. The logistic regression models were adjusted for marital status, country of origin, income, previous disease and previous accidents. RESULTS: Using psychotropic drugs was associated with increased odds for a falling accident in all age groups, however, with a dose-response relationship only among the elderly. Furthermore, using psychotropic drugs was associated with increased odds of transportation accidents in the ages 18-34 years and 35-64 years, respectively, but with a weaker association among the elderly. A similar pattern of association was seen for specific groups of psychotropic drugs: opioids, anti-depressants and anxiolytics/hypnotics/sedatives. CONCLUSIONS: In this total population-based study, there were nearly consistent associations between use of psychotropic drugs and injuries from falling accidents and transportation accidents, even after adjustment for previous accidents, previous disease and socio-demographic variables.},
  author       = {Modén, Birgit and Ohlsson, Henrik and Merlo, Juan and Rosvall, Maria},
  issn         = {1101-1262},
  language     = {eng},
  month        = {09},
  publisher    = {Oxford University Press},
  series       = {European Journal of Public Health},
  title        = {Psychotropic drugs and accidents in Scania, Sweden.},
  url          = {http://dx.doi.org/10.1093/eurpub/ckr110},
  year         = {2011},
}