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RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

Huang, Po-Ssu ; Ban, Yih-En Andrew ; Richter, Florian ; André, Ingemar LU orcid ; Vernon, Robert ; Schief, William R. and Baker, David (2011) In PLoS ONE 6(8).
Abstract
We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling.
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
6
issue
8
publisher
Public Library of Science (PLoS)
external identifiers
  • wos:000294680800055
  • scopus:80052334922
  • pmid:21909381
ISSN
1932-6203
DOI
10.1371/journal.pone.0024109
language
English
LU publication?
yes
id
581e61a0-9c5e-43a0-bf9e-7699edf38395 (old id 2183618)
date added to LUP
2016-04-01 14:33:17
date last changed
2021-10-03 03:24:34
@article{581e61a0-9c5e-43a0-bf9e-7699edf38395,
  abstract     = {We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling.},
  author       = {Huang, Po-Ssu and Ban, Yih-En Andrew and Richter, Florian and André, Ingemar and Vernon, Robert and Schief, William R. and Baker, David},
  issn         = {1932-6203},
  language     = {eng},
  number       = {8},
  publisher    = {Public Library of Science (PLoS)},
  series       = {PLoS ONE},
  title        = {RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design},
  url          = {http://dx.doi.org/10.1371/journal.pone.0024109},
  doi          = {10.1371/journal.pone.0024109},
  volume       = {6},
  year         = {2011},
}