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Approach to combine electron-beam lithography and two-photon polymerization for enhanced nano-channels in network-based biocomputation devices

Heldt, G.; Meinecke, Ch; Steenhusen, S.; Korten, T.; Groß, M.; Domann, G.; Lindberg, F. LU ; Reuter, D.; Dietz, St and Linke, H. LU , et al. (2018) 34th European Mask and Lithography Conference, EMLC 2018 10775.
Abstract

Although conventional computer technology made a huge leap forward in the past decade, a vast number of computational problems remain inaccessible due to their inherently complex nature. One solution to deal with this computational complexity is to highly parallelize computations and to explore new technologies beyond semiconductor computers. Here, we report on initial results leading to a device employing a biological computation approach called network-based biocomputation (NBC). So far, the manufacturing process relies on conventional Electron Beam Lithography (EBL). However we show first promising results expanding EBL patterning to the third dimension by employing Two-Photon Polymerization (2PP). The nanofabricated structures rely... (More)

Although conventional computer technology made a huge leap forward in the past decade, a vast number of computational problems remain inaccessible due to their inherently complex nature. One solution to deal with this computational complexity is to highly parallelize computations and to explore new technologies beyond semiconductor computers. Here, we report on initial results leading to a device employing a biological computation approach called network-based biocomputation (NBC). So far, the manufacturing process relies on conventional Electron Beam Lithography (EBL). However we show first promising results expanding EBL patterning to the third dimension by employing Two-Photon Polymerization (2PP). The nanofabricated structures rely on a combination of physical and chemical guiding of the microtubules through channels. Microtubules travelling through the network make their way through a number of different junctions. Here it is imperative that they do not take wrong turns. In order to decrease the usage of erroneous paths in the network a transition from planar 2-dimensional (mesh structure) networks to a design in which the crossing points of the mesh extend into the 3rd dimension is made. EBL is used to fabricate the 2D network structure whereas for the 3D-junctions 2PP is used. The good adaptation of the individual technologies allows for the possibility of a future combination of the two complementary approaches.

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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
error-free junctions, Network-based biocomputation, two-photon polymerization
host publication
34th European Mask and Lithography Conference
editor
Behringer, Uwe F.W.; Finders, Jo; and
volume
10775
publisher
SPIE
conference name
34th European Mask and Lithography Conference, EMLC 2018
conference location
Grenoble, France
conference dates
2018-06-18 - 2018-06-20
external identifiers
  • scopus:85054647952
ISBN
9781510621213
DOI
10.1117/12.2326598
language
English
LU publication?
yes
id
22085286-5e36-4adf-b698-e4d10627020e
date added to LUP
2018-11-13 14:28:27
date last changed
2019-02-20 11:35:38
@inproceedings{22085286-5e36-4adf-b698-e4d10627020e,
  abstract     = {<p>Although conventional computer technology made a huge leap forward in the past decade, a vast number of computational problems remain inaccessible due to their inherently complex nature. One solution to deal with this computational complexity is to highly parallelize computations and to explore new technologies beyond semiconductor computers. Here, we report on initial results leading to a device employing a biological computation approach called network-based biocomputation (NBC). So far, the manufacturing process relies on conventional Electron Beam Lithography (EBL). However we show first promising results expanding EBL patterning to the third dimension by employing Two-Photon Polymerization (2PP). The nanofabricated structures rely on a combination of physical and chemical guiding of the microtubules through channels. Microtubules travelling through the network make their way through a number of different junctions. Here it is imperative that they do not take wrong turns. In order to decrease the usage of erroneous paths in the network a transition from planar 2-dimensional (mesh structure) networks to a design in which the crossing points of the mesh extend into the 3rd dimension is made. EBL is used to fabricate the 2D network structure whereas for the 3D-junctions 2PP is used. The good adaptation of the individual technologies allows for the possibility of a future combination of the two complementary approaches.</p>},
  author       = {Heldt, G. and Meinecke, Ch and Steenhusen, S. and Korten, T. and Groß, M. and Domann, G. and Lindberg, F. and Reuter, D. and Dietz, St and Linke, H. and Schulz, St E.},
  editor       = {Behringer, Uwe F.W. and Finders, Jo},
  isbn         = {9781510621213},
  keyword      = {error-free junctions,Network-based biocomputation,two-photon polymerization},
  language     = {eng},
  location     = {Grenoble, France},
  publisher    = {SPIE},
  title        = {Approach to combine electron-beam lithography and two-photon polymerization for enhanced nano-channels in network-based biocomputation devices},
  url          = {http://dx.doi.org/10.1117/12.2326598},
  volume       = {10775},
  year         = {2018},
}