3D geometric gel dosimetry verification of intraprostatic fiducial guided hypofractionated radiotherapy of prostate cancer
Nordström, Fredrik LU ; Ceberg, Sofie LU ; af Wetterstedt, Sacha ; Nilsson, Per LU
; Ceberg, Crister
LU
and Bäck, Sven
LU
(2010)
IC3DDose: The 6th International Conference on 3D Radiation Dosimetry
250.
- Abstract
- This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of... (More)
- This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of the 95% isosurface of the TPS calculated dose distribution and the measured dose distribution using gel showed good agreement. The clinical target volume (CTV) was well centred inside the 95% isodose surface of the measured volume. It was shown for the evaluated case that the use of on-board imaging and integrated setup correction tools could be used to compensate for a deliberately introduced offset in CTV position. The study showed that MRI based nPAG gel dosimetry can be used to verify setup correction procedures using implanted gold fiducials. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2213096
- author
- Nordström, Fredrik
LU
; Ceberg, Sofie
LU
; af Wetterstedt, Sacha
; Nilsson, Per
LU
; Ceberg, Crister
LU
and Bäck, Sven
LU
- organization
- publishing date
- 2010
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- 3D verification, radiotherapy, polymer gel
- host publication
- Journal of Physics: Conference Series
- volume
- 250
- publisher
- IOP Publishing
- conference name
- IC3DDose: The 6th International Conference on 3D Radiation Dosimetry
- conference location
- Hilton Head Island, South Carolina, United States
- conference dates
- 2010-08-22
- external identifiers
-
- scopus:78650535940
- DOI
- 10.1088/1742-6596/250/1/012059
- language
- English
- LU publication?
- yes
- id
- cbe399c6-8873-4772-beeb-089e7fb86709 (old id 2213096)
- alternative location
- http://iopscience.iop.org/1742-6596/250/1/012059
- date added to LUP
- 2016-04-04 11:59:33
- date last changed
- 2022-01-29 22:47:10
@inproceedings{cbe399c6-8873-4772-beeb-089e7fb86709,
abstract = {{This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of the 95% isosurface of the TPS calculated dose distribution and the measured dose distribution using gel showed good agreement. The clinical target volume (CTV) was well centred inside the 95% isodose surface of the measured volume. It was shown for the evaluated case that the use of on-board imaging and integrated setup correction tools could be used to compensate for a deliberately introduced offset in CTV position. The study showed that MRI based nPAG gel dosimetry can be used to verify setup correction procedures using implanted gold fiducials.}},
author = {{Nordström, Fredrik and Ceberg, Sofie and af Wetterstedt, Sacha and Nilsson, Per and Ceberg, Crister and Bäck, Sven}},
booktitle = {{Journal of Physics: Conference Series}},
keywords = {{3D verification; radiotherapy; polymer gel}},
language = {{eng}},
publisher = {{IOP Publishing}},
title = {{3D geometric gel dosimetry verification of intraprostatic fiducial guided hypofractionated radiotherapy of prostate cancer}},
url = {{http://dx.doi.org/10.1088/1742-6596/250/1/012059}},
doi = {{10.1088/1742-6596/250/1/012059}},
volume = {{250}},
year = {{2010}},
}