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Some applications of ultrashort laser pulses in biology and medicine

Svanberg, Sune LU (2001) In Measurement Science & Technology 12(11). p.1777-1783
Abstract
Ultrashort laser pulses are finding increasing applications in biology and medicine. Such pulses can be used directly or after non-linear modification. Direct utilization includes propagation studies in scattering media with applications in optical mammography, dosimetry for photodynamic therapy and species concentration assessment. Intense continua of electromagnetic radiation of very brief duration are formed in the interaction of focused ultrashort and intense laser pulses with matter. Two different kinds of experiment using such radiation are described, employing visible radiation and x-rays, respectively. Focusing into water leads to the generation of a light continuum through self-phase modulation. The propagation of the light... (More)
Ultrashort laser pulses are finding increasing applications in biology and medicine. Such pulses can be used directly or after non-linear modification. Direct utilization includes propagation studies in scattering media with applications in optical mammography, dosimetry for photodynamic therapy and species concentration assessment. Intense continua of electromagnetic radiation of very brief duration are formed in the interaction of focused ultrashort and intense laser pulses with matter. Two different kinds of experiment using such radiation are described, employing visible radiation and x-rays, respectively. Focusing into water leads to the generation of a light continuum through self-phase modulation. The propagation of the light through tissue was studied, addressing questions related to specific tissue chromophore absorption. When terawatt laser pulses are focused onto a solid target with high nuclear charge Z, intense x-ray radiation of few ps duration and with energies exceeding hundreds of keV is emitted. Biomedical applications of this radiation are described, including differential absorption and gated-viewing imaging. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Measurement Science & Technology
volume
12
issue
11
pages
1777 - 1783
publisher
IOP Publishing
external identifiers
  • scopus:0035504376
ISSN
0957-0233
DOI
10.1088/0957-0233/12/11/304
language
English
LU publication?
yes
id
fe343984-5d14-41de-8333-a7b05efa1310 (old id 2259502)
date added to LUP
2012-02-07 09:50:48
date last changed
2017-08-13 04:42:30
@article{fe343984-5d14-41de-8333-a7b05efa1310,
  abstract     = {Ultrashort laser pulses are finding increasing applications in biology and medicine. Such pulses can be used directly or after non-linear modification. Direct utilization includes propagation studies in scattering media with applications in optical mammography, dosimetry for photodynamic therapy and species concentration assessment. Intense continua of electromagnetic radiation of very brief duration are formed in the interaction of focused ultrashort and intense laser pulses with matter. Two different kinds of experiment using such radiation are described, employing visible radiation and x-rays, respectively. Focusing into water leads to the generation of a light continuum through self-phase modulation. The propagation of the light through tissue was studied, addressing questions related to specific tissue chromophore absorption. When terawatt laser pulses are focused onto a solid target with high nuclear charge Z, intense x-ray radiation of few ps duration and with energies exceeding hundreds of keV is emitted. Biomedical applications of this radiation are described, including differential absorption and gated-viewing imaging.},
  author       = {Svanberg, Sune},
  issn         = {0957-0233},
  language     = {eng},
  number       = {11},
  pages        = {1777--1783},
  publisher    = {IOP Publishing},
  series       = {Measurement Science & Technology},
  title        = {Some applications of ultrashort laser pulses in biology and medicine},
  url          = {http://dx.doi.org/10.1088/0957-0233/12/11/304},
  volume       = {12},
  year         = {2001},
}