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Determination of left ventricular long-axis orientation using MRI: changes during the respiratory and cardiac cycles in normal and diseased subjects

Foster, J E; Engblom, Henrik LU ; Martin, T N; Wagner, G S; Steedman, T; Ferrua, S; Elliott, A T; Dargie, H J and Groenning, B A (2005) In Clinical Physiology and Functional Imaging 25(5). p.286-292
Abstract
Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes... (More)
Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes during the cardiac cycle were assessed in six subjects from each subject group. Reproducibility was assessed by a re-examination of 17 subjects after 28 days. Results: The inter- and intra-observer variability for LV long-axis orientation was low for all subject groups. The difference between the baseline and the 28 days examinations was -1.4 +/- 5.9 degrees and -0.8 +/- 4.4 degrees in the frontal and transverse planes, respectively. No significant change in LV long-axis orientation was found between end-expiration and end-inspiration (frontal plane, P = 0.63 and transverse plane, P = 0.42; n = 25). No significant difference in change of the LV long-axis orientation during the cardiac cycle was found between the subject groups (frontal plane, chi-square 1.8, P = 0.40 and transverse plane, chi-square 5.7, P = 0.06). Conclusions: There is a low inter-and intra-observer variability and a high reproducibility for determining LV long-axis orientation in patients with no cardiac disease as well as in patients with ACS or CHF. There is no significant change in LV long-axis orientation due to respiration, and only small changes during the cardiac cycle in these groups. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
LV long axis orientation, magnetic resonance imaging
in
Clinical Physiology and Functional Imaging
volume
25
issue
5
pages
286 - 292
publisher
Wiley Online Library
external identifiers
  • wos:000231262200006
  • pmid:16117732
  • scopus:24044543935
ISSN
1475-0961
DOI
10.1111/j.1475-097X.2005.00624.x
language
English
LU publication?
yes
id
c6f20424-3988-4552-a64d-5e7678d43508 (old id 229333)
date added to LUP
2007-08-08 15:00:15
date last changed
2017-07-09 03:42:12
@article{c6f20424-3988-4552-a64d-5e7678d43508,
  abstract     = {Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes during the cardiac cycle were assessed in six subjects from each subject group. Reproducibility was assessed by a re-examination of 17 subjects after 28 days. Results: The inter- and intra-observer variability for LV long-axis orientation was low for all subject groups. The difference between the baseline and the 28 days examinations was -1.4 +/- 5.9 degrees and -0.8 +/- 4.4 degrees in the frontal and transverse planes, respectively. No significant change in LV long-axis orientation was found between end-expiration and end-inspiration (frontal plane, P = 0.63 and transverse plane, P = 0.42; n = 25). No significant difference in change of the LV long-axis orientation during the cardiac cycle was found between the subject groups (frontal plane, chi-square 1.8, P = 0.40 and transverse plane, chi-square 5.7, P = 0.06). Conclusions: There is a low inter-and intra-observer variability and a high reproducibility for determining LV long-axis orientation in patients with no cardiac disease as well as in patients with ACS or CHF. There is no significant change in LV long-axis orientation due to respiration, and only small changes during the cardiac cycle in these groups.},
  author       = {Foster, J E and Engblom, Henrik and Martin, T N and Wagner, G S and Steedman, T and Ferrua, S and Elliott, A T and Dargie, H J and Groenning, B A},
  issn         = {1475-0961},
  keyword      = {LV long axis orientation,magnetic resonance imaging},
  language     = {eng},
  number       = {5},
  pages        = {286--292},
  publisher    = {Wiley Online Library},
  series       = {Clinical Physiology and Functional Imaging},
  title        = {Determination of left ventricular long-axis orientation using MRI: changes during the respiratory and cardiac cycles in normal and diseased subjects},
  url          = {http://dx.doi.org/10.1111/j.1475-097X.2005.00624.x},
  volume       = {25},
  year         = {2005},
}