Determination of left ventricular long-axis orientation using MRI: changes during the respiratory and cardiac cycles in normal and diseased subjects
(2005) In Clinical Physiology and Functional Imaging 25(5). p.286-292- Abstract
- Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes... (More)
- Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes during the cardiac cycle were assessed in six subjects from each subject group. Reproducibility was assessed by a re-examination of 17 subjects after 28 days. Results: The inter- and intra-observer variability for LV long-axis orientation was low for all subject groups. The difference between the baseline and the 28 days examinations was -1.4 +/- 5.9 degrees and -0.8 +/- 4.4 degrees in the frontal and transverse planes, respectively. No significant change in LV long-axis orientation was found between end-expiration and end-inspiration (frontal plane, P = 0.63 and transverse plane, P = 0.42; n = 25). No significant difference in change of the LV long-axis orientation during the cardiac cycle was found between the subject groups (frontal plane, chi-square 1.8, P = 0.40 and transverse plane, chi-square 5.7, P = 0.06). Conclusions: There is a low inter-and intra-observer variability and a high reproducibility for determining LV long-axis orientation in patients with no cardiac disease as well as in patients with ACS or CHF. There is no significant change in LV long-axis orientation due to respiration, and only small changes during the cardiac cycle in these groups. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/229333
- author
- Foster, J E ; Engblom, Henrik LU ; Martin, T N ; Wagner, G S ; Steedman, T ; Ferrua, S ; Elliott, A T ; Dargie, H J and Groenning, B A
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- LV long axis orientation, magnetic resonance imaging
- in
- Clinical Physiology and Functional Imaging
- volume
- 25
- issue
- 5
- pages
- 286 - 292
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000231262200006
- pmid:16117732
- scopus:24044543935
- ISSN
- 1475-0961
- DOI
- 10.1111/j.1475-097X.2005.00624.x
- language
- English
- LU publication?
- yes
- id
- c6f20424-3988-4552-a64d-5e7678d43508 (old id 229333)
- date added to LUP
- 2016-04-01 12:15:42
- date last changed
- 2022-01-27 01:11:55
@article{c6f20424-3988-4552-a64d-5e7678d43508,
abstract = {{Background: It has previously been shown that magnetic resonance imaging (MRI) can be used to accurately determine left ventricular (LV) long-axis orientation in healthy individuals. However, the inter- and intra-observer variability in patients with acute coronary syndrome (ACS) and chronic heart failure (CHF) has not been explored. Furthermore, the changes in LV long-axis orientation because of respiration and during the cardiac cycle remain to be determined. Methods: LV long-axis orientation was determined by MRI in the frontal and transverse planes in 44 subjects with no cardiac disease, 20 ACS patients and 13 CHF patients. Changes in LV long-axis orientation because of respiration were assessed in a subset of 25 subjects. Changes during the cardiac cycle were assessed in six subjects from each subject group. Reproducibility was assessed by a re-examination of 17 subjects after 28 days. Results: The inter- and intra-observer variability for LV long-axis orientation was low for all subject groups. The difference between the baseline and the 28 days examinations was -1.4 +/- 5.9 degrees and -0.8 +/- 4.4 degrees in the frontal and transverse planes, respectively. No significant change in LV long-axis orientation was found between end-expiration and end-inspiration (frontal plane, P = 0.63 and transverse plane, P = 0.42; n = 25). No significant difference in change of the LV long-axis orientation during the cardiac cycle was found between the subject groups (frontal plane, chi-square 1.8, P = 0.40 and transverse plane, chi-square 5.7, P = 0.06). Conclusions: There is a low inter-and intra-observer variability and a high reproducibility for determining LV long-axis orientation in patients with no cardiac disease as well as in patients with ACS or CHF. There is no significant change in LV long-axis orientation due to respiration, and only small changes during the cardiac cycle in these groups.}},
author = {{Foster, J E and Engblom, Henrik and Martin, T N and Wagner, G S and Steedman, T and Ferrua, S and Elliott, A T and Dargie, H J and Groenning, B A}},
issn = {{1475-0961}},
keywords = {{LV long axis orientation; magnetic resonance imaging}},
language = {{eng}},
number = {{5}},
pages = {{286--292}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology and Functional Imaging}},
title = {{Determination of left ventricular long-axis orientation using MRI: changes during the respiratory and cardiac cycles in normal and diseased subjects}},
url = {{http://dx.doi.org/10.1111/j.1475-097X.2005.00624.x}},
doi = {{10.1111/j.1475-097X.2005.00624.x}},
volume = {{25}},
year = {{2005}},
}